DNA repair by bacterial AlkB proteins - PubMed (original) (raw)

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DNA repair by bacterial AlkB proteins

Pål Ø Falnes et al. Res Microbiol. 2003 Oct.

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Abstract

The Escherichia coli AlkB protein is an iron- and 2-oxoglutarate-dependent oxygenase, repairing 1-methyladenine and 3-methylcytosine lesions in DNA. AlkB homologues are present in a number of bacterial species, and some bacteria have two different AlkB proteins. AlkB also repairs lesions in RNA, and the biological significance of RNA repair is discussed.

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