Dissociable stages of human memory consolidation and reconsolidation - PubMed (original) (raw)
Clinical Trial
. 2003 Oct 9;425(6958):616-20.
doi: 10.1038/nature01930.
Affiliations
- PMID: 14534587
- DOI: 10.1038/nature01930
Clinical Trial
Dissociable stages of human memory consolidation and reconsolidation
Matthew P Walker et al. Nature. 2003.
Abstract
Historically, the term 'memory consolidation' refers to a process whereby a memory becomes increasingly resistant to interference from competing or disrupting factors with the continued passage of time. Recent findings regarding the learning of skilled sensory and motor tasks ('procedural learning') have refined this definition, suggesting that consolidation can be more strictly determined by time spent in specific brain states such as wake, sleep or certain stages of sleep. There is also renewed interest in the possibility that recalling or 'reactivating' a previously consolidated memory renders it once again fragile and susceptible to interference, therefore requiring periods of reconsolidation. Using a motor skill finger-tapping task, here we provide evidence for at least three different stages of human motor memory processing after initial acquisition. We describe the unique contributions of wake and sleep in the development of different forms of consolidation, and show that waking reactivation can turn a previously consolidated memory back into a labile state requiring subsequent reconsolidation.
Comment in
- Neuroscience: re-recording human memories.
Nader K. Nader K. Nature. 2003 Oct 9;425(6958):571-2. doi: 10.1038/425571a. Nature. 2003. PMID: 14534572 No abstract available.
Similar articles
- Declarative interference affects off-line processing of motor imagery learning during both sleep and wakefulness.
Debarnot U, Castellani E, Guillot A, Giannotti V, Dimarco M, Sebastiani L. Debarnot U, et al. Neurobiol Learn Mem. 2012 Nov;98(4):361-7. doi: 10.1016/j.nlm.2012.10.009. Epub 2012 Oct 26. Neurobiol Learn Mem. 2012. PMID: 23103616 - Sleep's role in the reconsolidation of declarative memories.
Klinzing JG, Rasch B, Born J, Diekelmann S. Klinzing JG, et al. Neurobiol Learn Mem. 2016 Dec;136:166-173. doi: 10.1016/j.nlm.2016.10.004. Epub 2016 Oct 6. Neurobiol Learn Mem. 2016. PMID: 27720856 - Sleep Spindles Preferentially Consolidate Weakly Encoded Memories.
Denis D, Mylonas D, Poskanzer C, Bursal V, Payne JD, Stickgold R. Denis D, et al. J Neurosci. 2021 May 5;41(18):4088-4099. doi: 10.1523/JNEUROSCI.0818-20.2021. Epub 2021 Mar 19. J Neurosci. 2021. PMID: 33741722 Free PMC article. - Sleep-dependent memory consolidation and reconsolidation.
Stickgold R, Walker MP. Stickgold R, et al. Sleep Med. 2007 Jun;8(4):331-43. doi: 10.1016/j.sleep.2007.03.011. Epub 2007 Apr 30. Sleep Med. 2007. PMID: 17470412 Free PMC article. Review. - Sharp-wave ripples as a signature of hippocampal-prefrontal reactivation for memory during sleep and waking states.
Tang W, Jadhav SP. Tang W, et al. Neurobiol Learn Mem. 2019 Apr;160:11-20. doi: 10.1016/j.nlm.2018.01.002. Epub 2018 Jan 10. Neurobiol Learn Mem. 2019. PMID: 29331447 Free PMC article. Review.
Cited by
- Unraveling the time-of-day influences on motor consolidation through the motor-declarative memory conflict.
Truong C, Papaxanthis C, Ruffino C. Truong C, et al. Sci Rep. 2024 Sep 27;14(1):22195. doi: 10.1038/s41598-024-69336-0. Sci Rep. 2024. PMID: 39333514 Free PMC article. - Distinct Neural Plasticity Enhancing Visual Perception.
Kondat T, Tik N, Sharon H, Tavor I, Censor N. Kondat T, et al. J Neurosci. 2024 Sep 4;44(36):e0301242024. doi: 10.1523/JNEUROSCI.0301-24.2024. J Neurosci. 2024. PMID: 39103221 - Counterfactual thinking induces different neural patterns of memory modification in anxious individuals.
Huang S, Faul L, Parikh N, LaBar KS, De Brigard F. Huang S, et al. Sci Rep. 2024 May 9;14(1):10630. doi: 10.1038/s41598-024-61545-x. Sci Rep. 2024. PMID: 38724623 Free PMC article. - Action sequence learning, habits, and automaticity in obsessive-compulsive disorder.
Banca P, Herrojo Ruiz M, Gonzalez-Zalba MF, Biria M, Marzuki AA, Piercy T, Sule A, Fineberg NA, Robbins TW. Banca P, et al. Elife. 2024 May 9;12:RP87346. doi: 10.7554/eLife.87346. Elife. 2024. PMID: 38722306 Free PMC article. - Engram mechanisms of memory linking and identity.
Choucry A, Nomoto M, Inokuchi K. Choucry A, et al. Nat Rev Neurosci. 2024 Jun;25(6):375-392. doi: 10.1038/s41583-024-00814-0. Epub 2024 Apr 25. Nat Rev Neurosci. 2024. PMID: 38664582 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical