Do disorders of movement cause movement disorders and dementia? - PubMed (original) (raw)

Review

. 2003 Oct 9;40(2):415-25.

doi: 10.1016/s0896-6273(03)00630-5.

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Review

Do disorders of movement cause movement disorders and dementia?

Lawrence S B Goldstein. Neuron. 2003.

Free article

Abstract

Neurons require long-distance microtubule-based transport systems to ferry vital cellular cargoes and signals between cell bodies and axonal or dendritic terminals. Considerable progress has been made on developing a molecular understanding of these processes and how they are integrated into normal neuronal functions. Recent work also suggests that these transport systems may fail early in the pathogenesis of a number of neurodegenerative diseases.

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