Ipsilateral fast corticospinal pathways do not account for recovery in stroke - PubMed (original) (raw)

Ipsilateral fast corticospinal pathways do not account for recovery in stroke

E Palmer et al. Ann Neurol. 1992 Oct.

Abstract

We tested the hypothesis that in adult humans, recovery from stroke results from the emergence of ipsilateral, fast-conducting corticospinal pathways. In 10 patients recovering from stroke, the unaffected hemisphere was stimulated with an electromagnet and changes in the firing probability of single biceps motor units were used to derive postsynaptic potentials in single biceps motoneurons. Stimuli sufficient to excite the neurons of the fast-conducting corticospinal pathway (as shown by short-latency facilitation of contralateral biceps motoneurons) did not produce short-latency depolarization of ipsilateral biceps motoneurons. The hypothesis is therefore not supported.

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Comment in

• Emerging ipsilateral corticospinal pathways after stroke?
  van den Brink AM, van der Kamp W, van Dijk JG. van den Brink AM, et al. Ann Neurol. 1994 Sep;36(3):448-9. doi: 10.1002/ana.410360319. Ann Neurol. 1994. PMID: 8080255 No abstract available.

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