Gamma oscillations correlate with working memory load in humans - PubMed (original) (raw)
Case Reports
. 2003 Dec;13(12):1369-74.
doi: 10.1093/cercor/bhg084.
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- PMID: 14615302
- DOI: 10.1093/cercor/bhg084
Case Reports
Gamma oscillations correlate with working memory load in humans
Marc W Howard et al. Cereb Cortex. 2003 Dec.
Abstract
Functional imaging of human cortex implicates a diverse network of brain regions supporting working memory - the capacity to hold and manipulate information for short periods of time. Although we are beginning to map out the brain networks supporting working memory, little is known about its physiological basis. We analyzed intracranial recordings from two epileptic patients as they performed a working memory task. Spectral analyses revealed that, in both patients, gamma (30-60 Hz) oscillations increased approximately linearly with memory load, tracking closely with memory load over the course of the trial. This constitutes the first evidence that gamma oscillations, widely implicated in perceptual processes, support the maintenance of multiple items in working memory.
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