Sleep-dependent theta oscillations in the human hippocampus and neocortex - PubMed (original) (raw)

Figure 5.

Evidence of different θ generator sources within the human hippocampal formation and neocortex. A, Averaged partial coherence results between pairs of electrodes for each wake-sleep state after removing common influences from other sources. Electrode pairs were located within the hippocampal formation (hipp-hipp; coordinates: 24.0, -26.9, -7.2; and 24.0, -36.2, 3.1), the basal surface of the temporal lobe (ctx-ctx; coordinates: -29.0, 0.4, -27.4; and -43.8, -38.3, -14.6), or had one electrode in each structure (hipp-ctx; coordinates: 24.0, -26.9, -7.2; and -29.0, 0.4, -27.4). B, Comparison of averaged θ power (4-7 Hz) within hippocampus and neocortex for each wake-sleep state. Data are from the same subject as in A. C, Same as A, but for a different patient. Corticocortical coupling in this patient was determined using a pair of electrodes located in the frontal lobe. Talairach coordinates (in mm): hipp-hipp, 24.0, -32.1, -0.8, and 24.0, -15.7, -12.1; ctx-ctx, 14.8, 13.3, 41.2, and 25.0, 21.9, 31.2; hipp-ctx, 24.0, -32.1, -0.8, and 14.8, 13.3, 41.2. D, Same as B, but for the patient shown in C. Results for both partial coherence and spectral analysis were essentially unchanged when other combinations of electrodes were used in each patient.