Regulation of isotype switching - PubMed (original) (raw)

Review

Regulation of isotype switching

D Vercelli et al. Curr Opin Immunol. 1992 Dec.

Abstract

In the past year, our understanding of the mechanisms that regulate isotype switching has significantly progressed. Activation of germ line transcription by isotype-specific cytokines is emerging as a crucial mechanism for increasing the accessibility of a particular switch region, and targeting switch recombination.

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