NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner - PubMed (original) (raw)

• Skewed epithelial cell differentiation and premature aging of the thymus in the absence of vitamin D signaling.
  Artusa P, Nguyen Yamamoto L, Barbier C, Valbon SF, Aghazadeh Habashi Y, Djambazian H, Ismailova A, Lebel MÈ, Salehi-Tabar R, Sarmadi F, Ragoussis J, Goltzman D, Melichar HJ, White JH. Artusa P, et al. Sci Adv. 2024 Sep 27;10(39):eadm9582. doi: 10.1126/sciadv.adm9582. Epub 2024 Sep 25. Sci Adv. 2024. PMID: 39321290 Free PMC article.
• Not just for lymphoid cells: the role of the noncanonical NF-κB signaling pathway in early and late myelopoiesis with a focus on hypereosinophilic disorders.
  Trusiano B, Zimmerman KL, Morrison HA, Allen IC. Trusiano B, et al. J Leukoc Biol. 2024 Jul 25;116(2):297-306. doi: 10.1093/jleuko/qiae101. J Leukoc Biol. 2024. PMID: 38682253 Review.
• Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity.
  Takakura Y, Machida M, Terada N, Katsumi Y, Kawamura S, Horie K, Miyauchi M, Ishikawa T, Akiyama N, Seki T, Miyao T, Hayama M, Endo R, Ishii H, Maruyama Y, Hagiwara N, Kobayashi TJ, Yamaguchi N, Takano H, Akiyama T, Yamaguchi N. Takakura Y, et al. Nat Commun. 2024 Feb 1;15(1):953. doi: 10.1038/s41467-024-45206-1. Nat Commun. 2024. PMID: 38296961 Free PMC article.
• Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency.
  Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillani-Dalbin P, Charuel JL, Philippot Q, Gueye MS, Maglorius Renkilaraj MRL, Ogishi M, Soudée C, Migaud M, Rozenberg F, Momenilandi M, Riller Q, Imberti L, Delmonte OM, Müller G, Keller B, Orrego J, Franco Gallego WA, Rubin T, Emiroglu M, Parvaneh N, Eriksson D, Aranda-Guillen M, Berrios DI, Vong L, Katelaris CH, Mustillo P, Raedler J, Bohlen J, Bengi Celik J, Astudillo C, Winter S; NF-κB Consortium; COVID Human Genetic Effort; McLean C, Guffroy A, DeRisi JL, Yu D, Miller C, Feng Y, Guichard A, Béziat V, Bustamante J, Pan-Hammarström Q, Zhang Y, Rosen LB, Holland SM, Bosticardo M, Kenney H, Castagnoli R, Slade CA, Boztuğ K, Mahlaoui N, Latour S, Abraham RS, Lougaris V, Hauck F, Sediva A, Atschekzei F, Sogkas G, Poli MC, Slatter MA, Palterer B, Keller MD, Pinzon-Charry A, Sullivan A, Droney L, Suan D, Wong M, Kane A, Hu H, Ma C, Grombiříková H, Ciznar P, Dalal I, Aladjidi N, Hie M, Lazaro E, Franco J, Keles S, Malphettes M, Pasquet M, Maccari ME, Meinhardt A, Ikinciogullari A, Shahrooei M, Celmeli F, Frosk P, Goodnow CC, Gray PE, Bel… See abstract for full author list ➔ Le Voyer T, et al. Nature. 2023 Nov;623(7988):803-813. doi: 10.1038/s41586-023-06717-x. Epub 2023 Nov 8. Nature. 2023. PMID: 37938781 Free PMC article.
• Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis.
  Farley AM, Chengrui A, Palmer S, Liu D, Kousa AI, Rouse P, Major V, Sweetman J, Morys J, Corsinotti A, Nichols J, Ure J, McLay R, Boulter L, Chapman SJ, Tomlinson SR, Blackburn CC. Farley AM, et al. Front Immunol. 2023 Jul 25;14:1202163. doi: 10.3389/fimmu.2023.1202163. eCollection 2023. Front Immunol. 2023. PMID: 37559721 Free PMC article.