Regulation of notch signaling activity - PubMed (original) (raw)

Review

. 2004 Feb 3;14(3):R129-38.

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• PMID: 14986688

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Review

Regulation of notch signaling activity

François Schweisguth. Curr Biol. 2004.

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Abstract

Cell-cell signalling mediated by the receptor Notch is used widely across the metazoans to determine cell fate and regulate pattern formation. Notch signals via a conserved regulated intramembrane proteolysis. Recent analyses of the cell biology of the Notch receptor have identified several fundamental mechanisms that contribute to regulate Notch signaling activity in space and time.

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