The two-process model of sleep regulation revisited - PubMed (original) (raw)
Review
. 2004 Mar;75(3 Suppl):A37-43.
Affiliations
- PMID: 15018264
Review
The two-process model of sleep regulation revisited
Peter Achermann. Aviat Space Environ Med. 2004 Mar.
Abstract
The two-process model of sleep regulation posits that the interaction of its two constituent processes, a sleep/wake dependent homeostatic Process S and a circadian Process C, generates the timing of sleep and waking. The time course of Process S was derived from a physiological variable, EEG slow-wave activity. In addition to the timing of sleep, changes of daytime vigilance are accounted for by the interaction of the two processes. The attractiveness of the model derives from its physiological basis and its mathematical simplicity. The two-process model stimulated the establishment of other models of neurobehavioral functions. The background of the model is reviewed and simulations of alertness and sleepiness are discussed.
Similar articles
- Regulation of adolescent sleep: implications for behavior.
Carskadon MA, Acebo C, Jenni OG. Carskadon MA, et al. Ann N Y Acad Sci. 2004 Jun;1021:276-91. doi: 10.1196/annals.1308.032. Ann N Y Acad Sci. 2004. PMID: 15251897 Review. - Sleep and sleep homeostasis in constant darkness in the rat.
Deboer T. Deboer T. J Sleep Res. 2009 Sep;18(3):357-64. doi: 10.1111/j.1365-2869.2008.00728.x. Epub 2009 Jun 22. J Sleep Res. 2009. PMID: 19552704 - Predictions from the three-process model of alertness.
Akerstedt T, Folkard S, Portin C. Akerstedt T, et al. Aviat Space Environ Med. 2004 Mar;75(3 Suppl):A75-83. Aviat Space Environ Med. 2004. PMID: 15018267 - Sleep homeostasis in the rat in the light and dark period.
Vyazovskiy VV, Achermann P, Tobler I. Vyazovskiy VV, et al. Brain Res Bull. 2007 Sep 14;74(1-3):37-44. doi: 10.1016/j.brainresbull.2007.05.001. Epub 2007 May 24. Brain Res Bull. 2007. PMID: 17683787 - Sleep, circadian rhythms, and delayed phase in adolescence.
Crowley SJ, Acebo C, Carskadon MA. Crowley SJ, et al. Sleep Med. 2007 Sep;8(6):602-12. doi: 10.1016/j.sleep.2006.12.002. Epub 2007 Mar 26. Sleep Med. 2007. PMID: 17383934 Review.
Cited by
- Concussion and the Sleeping Brain.
Donahue CC, Resch JE. Donahue CC, et al. Sports Med Open. 2024 Jun 9;10(1):68. doi: 10.1186/s40798-024-00736-2. Sports Med Open. 2024. PMID: 38853235 Free PMC article. Review. - Changes in Insomnia Severity are Associated With the Changes in Discrepancy Between Desired Time in Bed and Desired Total Sleep Time Among the General Population.
Chung S, Kim S, Cho IK, Lee D, Kim J, Cho E. Chung S, et al. Psychiatry Investig. 2023 Dec;20(12):1148-1156. doi: 10.30773/pi.2023.0220. Epub 2023 Dec 18. Psychiatry Investig. 2023. PMID: 38163654 Free PMC article. - Forecasting crew fatigue risk on international flights under different policies in China during the COVID-19 outbreak.
Junya S, Ruishan S. Junya S, et al. Front Public Health. 2022 Oct 18;10:996664. doi: 10.3389/fpubh.2022.996664. eCollection 2022. Front Public Health. 2022. PMID: 36330108 Free PMC article. - Flight crew fatigue risk assessment for international flights under the COVID-19 outbreak response exemption policy.
Sun J, Sun R, Li J, Wang P, Zhang N. Sun J, et al. BMC Public Health. 2022 Oct 1;22(1):1843. doi: 10.1186/s12889-022-14214-5. BMC Public Health. 2022. PMID: 36183066 Free PMC article. - Sleep's role in the development and resolution of adolescent depression.
Gradisar M, Kahn M, Micic G, Short M, Reynolds C, Orchard F, Bauducco S, Bartel K, Richardson C. Gradisar M, et al. Nat Rev Psychol. 2022;1(9):512-523. doi: 10.1038/s44159-022-00074-8. Epub 2022 Jun 20. Nat Rev Psychol. 2022. PMID: 35754789 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Other Literature Sources