The role of programming in memory T-cell development - PubMed (original) (raw)
Review
The role of programming in memory T-cell development
David Masopust et al. Curr Opin Immunol. 2004 Apr.
Abstract
Recent studies suggest that memory T-cell differentiation continues for weeks or months following antigen clearance, although commitment to the memory lineage occurs during the effector stage of development. Several variables associated with priming, such as the duration of antigenic stimulation, degree of co-stimulation, cytokine environment, and CD4(+) T-cell help, may program epigenetic qualitative differences into the ensuing effector and memory populations. Defining what memory qualities best protect the organism from re-infection, as well as how commitment to the memory lineage is specified following T-cell activation remains an important goal.
Similar articles
- Effector and memory T-cell differentiation: implications for vaccine development.
Kaech SM, Wherry EJ, Ahmed R. Kaech SM, et al. Nat Rev Immunol. 2002 Apr;2(4):251-62. doi: 10.1038/nri778. Nat Rev Immunol. 2002. PMID: 12001996 Review. - Memory CD4 T cells emerge from effector T-cell progenitors.
Harrington LE, Janowski KM, Oliver JR, Zajac AJ, Weaver CT. Harrington LE, et al. Nature. 2008 Mar 20;452(7185):356-60. doi: 10.1038/nature06672. Epub 2008 Mar 5. Nature. 2008. PMID: 18322463 - CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.
Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, Griffith TS, Green DR, Schoenberger SP. Janssen EM, et al. Nature. 2005 Mar 3;434(7029):88-93. doi: 10.1038/nature03337. Nature. 2005. PMID: 15744305 - Towards a cellular definition of CD8+ T-cell memory: the role of CD4+ T-cell help in CD8+ T-cell responses.
Rocha B, Tanchot C. Rocha B, et al. Curr Opin Immunol. 2004 Jun;16(3):259-63. doi: 10.1016/j.coi.2004.03.004. Curr Opin Immunol. 2004. PMID: 15134772 Review. - Similarities and differences in CD4+ and CD8+ effector and memory T cell generation.
Seder RA, Ahmed R. Seder RA, et al. Nat Immunol. 2003 Sep;4(9):835-42. doi: 10.1038/ni969. Nat Immunol. 2003. PMID: 12942084 Review.
Cited by
- Rituximab may affect T lymphocyte subsets balance in primary membranous nephropathy.
Zhang Y, Yang J, Li J, Sun J, Zhou L, Xu D, Sha W, Dai L, Shen L. Zhang Y, et al. BMC Nephrol. 2024 Mar 6;25(1):86. doi: 10.1186/s12882-024-03521-1. BMC Nephrol. 2024. PMID: 38448810 Free PMC article. - Efficacy of immune checkpoint inhibitors in non-small cell lung cancer with NTRK family mutations.
Shang X, Zhang W, Han W, Xia H, Liu N, Wang X, Liu Y. Shang X, et al. BMC Pulm Med. 2023 Nov 29;23(1):482. doi: 10.1186/s12890-023-02707-x. BMC Pulm Med. 2023. PMID: 38031067 Free PMC article. - Shaping immunity for life: Layered development of CD8+ T cells.
Tabilas C, Smith NL, Rudd BD. Tabilas C, et al. Immunol Rev. 2023 May;315(1):108-125. doi: 10.1111/imr.13185. Epub 2023 Jan 18. Immunol Rev. 2023. PMID: 36653953 Free PMC article. Review. - T cell responses to control fungal infection in an immunological memory lens.
Sharma J, Mudalagiriyappa S, Nanjappa SG. Sharma J, et al. Front Immunol. 2022 Sep 13;13:905867. doi: 10.3389/fimmu.2022.905867. eCollection 2022. Front Immunol. 2022. PMID: 36177012 Free PMC article. Review. - CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma.
Li M, Zhao J, Yang R, Cai R, Liu X, Xie J, Shu B, Qi S. Li M, et al. Cancer Sci. 2022 Apr;113(4):1220-1234. doi: 10.1111/cas.15303. Epub 2022 Mar 1. Cancer Sci. 2022. PMID: 35189004 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials