The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways - PubMed (original) (raw)
The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways
Corinne P Cluis et al. Plant J. 2004 Apr.
Free article
Abstract
The role of the Arabidopsis transcription factor LONG HYPOCOTYL 5 (HY5) in promoting photomorphogenic development has been extensively characterized. Although the current model for HY5 action largely explains its role in this process, it does not adequately address the root phenotype observed in hy5 mutants. In our search for common mechanisms underlying all hy5 traits, we found that they are partly the result of an altered balance of signaling through the plant hormones auxin and cytokinin. hy5 mutants are resistant to cytokinin application, and double mutant analyses indicate that a decrease in auxin signaling moderates hy5 phenotypes. Microarray analyses and semiquantitative RT-PCR indicate that two negative regulators of auxin signaling, AUXIN RESISTANT 2 (AXR2)/INDOLE ACETIC ACID 7 (IAA7) and SOLITARY ROOT (SLR)/IAA14, are underexpressed in hy5 mutants. The promoters of these genes contain a putative HY5 binding site, and in line with this observation, HY5 can bind to the promoter of AXR2 in vitro. Increased AXR2 expression in a hy5 background partially rescues the elongated hypocotyl phenotype. In summary, it appears that auxin signaling is elevated in hy5 mutants because HY5 promotes the expression of negative regulators of auxin signaling, thereby linking hormone and light signaling pathways.
Similar articles
- Tissue-specific expression of stabilized SOLITARY-ROOT/IAA14 alters lateral root development in Arabidopsis.
Fukaki H, Nakao Y, Okushima Y, Theologis A, Tasaka M. Fukaki H, et al. Plant J. 2005 Nov;44(3):382-95. doi: 10.1111/j.1365-313X.2005.02537.x. Plant J. 2005. PMID: 16236149 - Specificity and similarity of functions of the Aux/IAA genes in auxin signaling of Arabidopsis revealed by promoter-exchange experiments among MSG2/IAA19, AXR2/IAA7, and SLR/IAA14.
Muto H, Watahiki MK, Nakamoto D, Kinjo M, Yamamoto KT. Muto H, et al. Plant Physiol. 2007 May;144(1):187-96. doi: 10.1104/pp.107.096628. Epub 2007 Mar 16. Plant Physiol. 2007. PMID: 17369427 Free PMC article. - LZF1, a HY5-regulated transcriptional factor, functions in Arabidopsis de-etiolation.
Chang CS, Li YH, Chen LT, Chen WC, Hsieh WP, Shin J, Jane WN, Chou SJ, Choi G, Hu JM, Somerville S, Wu SH. Chang CS, et al. Plant J. 2008 Apr;54(2):205-19. doi: 10.1111/j.1365-313X.2008.03401.x. Epub 2008 Jan 7. Plant J. 2008. PMID: 18182030 - Funneling auxin action: specificity in signal transduction.
Weijers D, Jürgens G. Weijers D, et al. Curr Opin Plant Biol. 2004 Dec;7(6):687-93. doi: 10.1016/j.pbi.2004.09.006. Curr Opin Plant Biol. 2004. PMID: 15491917 Review. - Phytohormone collaboration: zooming in on auxin-brassinosteroid interactions.
Hardtke CS, Dorcey E, Osmont KS, Sibout R. Hardtke CS, et al. Trends Cell Biol. 2007 Oct;17(10):485-92. doi: 10.1016/j.tcb.2007.08.003. Epub 2007 Sep 29. Trends Cell Biol. 2007. PMID: 17904848 Review.
Cited by
- Regulatory Dynamics of Plant Hormones and Transcription Factors under Salt Stress.
Aizaz M, Lubna, Jan R, Asaf S, Bilal S, Kim KM, Al-Harrasi A. Aizaz M, et al. Biology (Basel). 2024 Aug 29;13(9):673. doi: 10.3390/biology13090673. Biology (Basel). 2024. PMID: 39336100 Free PMC article. Review. - Prefoldin Subunits and Its Associate Partners: Conservations and Specificities in Plants.
Yang Y, Zhang G, Su M, Shi Q, Chen Q. Yang Y, et al. Plants (Basel). 2024 Feb 18;13(4):556. doi: 10.3390/plants13040556. Plants (Basel). 2024. PMID: 38498526 Free PMC article. Review. - Red light induces salicylic acid accumulation by activating CaHY5 to enhance pepper resistance against Phytophthora capsici.
Yang Y, Li Y, Guang Y, Lin J, Zhou Y, Yu T, Ding F, Wang Y, Chen J, Zhou Y, Dang F. Yang Y, et al. Hortic Res. 2023 Oct 17;10(11):uhad213. doi: 10.1093/hr/uhad213. eCollection 2023 Nov. Hortic Res. 2023. PMID: 38046851 Free PMC article. - Arogenate dehydratases: unique roles in light-directed development during the seed-to-seedling transition in Arabidopsis thaliana.
Muhammad D, Alameldin HF, Oh S, Montgomery BL, Warpeha KM. Muhammad D, et al. Front Plant Sci. 2023 Aug 2;14:1220732. doi: 10.3389/fpls.2023.1220732. eCollection 2023. Front Plant Sci. 2023. PMID: 37600200 Free PMC article. - Auxin regulation on crop: from mechanisms to opportunities in soybean breeding.
Li L, Chen X. Li L, et al. Mol Breed. 2023 Mar 2;43(3):16. doi: 10.1007/s11032-023-01361-9. eCollection 2023 Mar. Mol Breed. 2023. PMID: 37313296 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases