VDJ recombination - PubMed (original) (raw)
Review
VDJ recombination
F W Alt et al. Immunol Today. 1992 Aug.
Abstract
The ability of lymphocyte receptor V, D and J gene segments to rearrange generates much of the receptor diversity that is the hallmark of the immune system. Naturally, the mechanisms of immunoglobulin and T-cell receptor gene recombination are of enormous interest. Here, Fred Alt and colleagues review current understanding of the process and speculate on future findings.
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