Nodal signaling: CrypticLefty mechanism of antagonism decoded - PubMed (original) (raw)
Review
. 2004 May 4;14(9):R341-3.
doi: 10.1016/j.cub.2004.04.020.
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- PMID: 15120085
- DOI: 10.1016/j.cub.2004.04.020
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Review
Nodal signaling: CrypticLefty mechanism of antagonism decoded
William W Branford et al. Curr Biol. 2004.
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Abstract
The secreted TGFbeta factor Lefty antagonizes Nodal signaling during vertebrate embryogenesis, but how it does so has been a mystery. Recent analyses have elucidated the molecular mechanisms underlying this function of Lefty.
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