A novel cost of R gene resistance in the presence of disease - PubMed (original) (raw)
. 2004 Apr;163(4):489-504.
doi: 10.1086/382552. Epub 2004 Mar 18.
Affiliations
- PMID: 15122498
- DOI: 10.1086/382552
A novel cost of R gene resistance in the presence of disease
Tonia Korves et al. Am Nat. 2004 Apr.
Abstract
Resistance responses can impose fitness costs when pests are absent. Here, we test whether the induction of resistance can decrease fitness even in plants under attack; we call this potential outcome a net cost with attack. Using lines in which genetic background was controlled, we investigated whether susceptible Arabidopsis thaliana plants can outperform R gene resistant plants when infected with pathogens. For the R gene RPS2, there was a fitness benefit of resistance in the presence of intraspecific competition, but there was a net cost in the absence of competition: resistant plants produced less seed than susceptible plants even though infected with Pseudomonas syringae. This net cost was primarily due to overcompensation by susceptible plants, which occurred because of a developmental response to infection. For the R gene RPP5, there was no fitness effect of resistance without competition but a net cost when plants were infected with Peronospora parasitica in the presence of competition. This net cost was due to a reduction in the fitness of infected, resistant plants and complete compensation in susceptible plants. A spatially variable model suggests that a trade-off between net benefits and net costs with attack may help explain the persistence of individuals lacking R gene resistance to disease.
Similar articles
- Quantitative fitness effects of infection in a gene-for-gene system.
Gao L, Roux F, Bergelson J. Gao L, et al. New Phytol. 2009 Oct;184(2):485-494. doi: 10.1111/j.1469-8137.2009.02959.x. Epub 2009 Jul 29. New Phytol. 2009. PMID: 19659661 Free PMC article. - Characterization of a novel, defense-related Arabidopsis mutant, cir1, isolated by luciferase imaging.
Murray SL, Thomson C, Chini A, Read ND, Loake GJ. Murray SL, et al. Mol Plant Microbe Interact. 2002 Jun;15(6):557-66. doi: 10.1094/MPMI.2002.15.6.557. Mol Plant Microbe Interact. 2002. PMID: 12059104 - A developmental response to pathogen infection in Arabidopsis.
Korves TM, Bergelson J. Korves TM, et al. Plant Physiol. 2003 Sep;133(1):339-47. doi: 10.1104/pp.103.027094. Plant Physiol. 2003. PMID: 12970499 Free PMC article. - The fitness costs to plants of resistance to pathogens.
Burdon JJ, Thrall PH. Burdon JJ, et al. Genome Biol. 2003;4(9):227. doi: 10.1186/gb-2003-4-9-227. Epub 2003 Aug 14. Genome Biol. 2003. PMID: 12952527 Free PMC article. Review. - Fitness costs of induced resistance: emerging experimental support for a slippery concept.
Heil M, Baldwin IT. Heil M, et al. Trends Plant Sci. 2002 Feb;7(2):61-7. doi: 10.1016/s1360-1385(01)02186-0. Trends Plant Sci. 2002. PMID: 11832276 Review.
Cited by
- Effects of pathogen exposure on life-history variation in the gypsy moth (Lymantria dispar).
Páez DJ, Fleming-Davies AE, Dwyer G. Páez DJ, et al. J Evol Biol. 2015 Oct;28(10):1828-39. doi: 10.1111/jeb.12699. Epub 2015 Aug 8. J Evol Biol. 2015. PMID: 26201381 Free PMC article. - Mutations in the NB-ARC domain of I-2 that impair ATP hydrolysis cause autoactivation.
Tameling WI, Vossen JH, Albrecht M, Lengauer T, Berden JA, Haring MA, Cornelissen BJ, Takken FL. Tameling WI, et al. Plant Physiol. 2006 Apr;140(4):1233-45. doi: 10.1104/pp.105.073510. Epub 2006 Feb 17. Plant Physiol. 2006. PMID: 16489136 Free PMC article. - Conditions under which genome-wide association studies will be positively misleading.
Platt A, Vilhjálmsson BJ, Nordborg M. Platt A, et al. Genetics. 2010 Nov;186(3):1045-52. doi: 10.1534/genetics.110.121665. Epub 2010 Sep 2. Genetics. 2010. PMID: 20813880 Free PMC article. - Population Genetics of the Highly Polymorphic RPP8 Gene Family.
MacQueen A, Tian D, Chang W, Holub E, Kreitman M, Bergelson J. MacQueen A, et al. Genes (Basel). 2019 Sep 8;10(9):691. doi: 10.3390/genes10090691. Genes (Basel). 2019. PMID: 31500388 Free PMC article. - Genomic analysis of QTLs and genes altering natural variation in stochastic noise.
Jimenez-Gomez JM, Corwin JA, Joseph B, Maloof JN, Kliebenstein DJ. Jimenez-Gomez JM, et al. PLoS Genet. 2011 Sep;7(9):e1002295. doi: 10.1371/journal.pgen.1002295. Epub 2011 Sep 29. PLoS Genet. 2011. PMID: 21980300 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous