Evaluation of the response to treatment of solid tumours - a consensus statement of the International Cancer Imaging Society - PubMed (original) (raw)

Review

Evaluation of the response to treatment of solid tumours - a consensus statement of the International Cancer Imaging Society

J E Husband et al. Br J Cancer. 2004.

Abstract

New guidelines to evaluate the response to treatment in solid tumors using imaging techniques have major limitations and important implications for radiological workload. This consensus statement from the International Cancer Imaging Society (ICIS) reviews the RECIST criteria and addresses several challenges regarding tumour measurement. Recommendations are made regarding tumour measurement and other issues are raised. The growing need to introduce a multimodality approach to monitoring response is recognized. ICIS welcomes a dialogue with the authors of RECIST to address issues raised in this review.

PubMed Disclaimer

Figures

Figure 1

Figure 1

Patient with non-small cell lung cancer on chemotherapy. Evidence of enlarged subcarinal lymph node measuring 3.4 × 2.9 cm at baseline (A), which has decreased in size to 3.4 × 2.0 cm at subsequent follow-up (B).

Figure 2

Figure 2

Partially calcified liver metastases from colorectal cancer imaged at baseline (A) and at a 6-week interval follow-up (B). The soft tissue masses surrounding the calcification have decreased in size – the overall mass including the calcification has either stayed stable or increased.

Figure 3

Figure 3

Visualisation of liver metastases is greatly influenced by phase of contrast administration. Note nonvisualisation of lesions in the equilibrium phase (A), which are seen in the arterial phase (B) (arrows).

References

    1. Belton AL, Saini S, Liebermann K, Boland GW, Halpern EF (2003) Tumor size measurement in an oncology clinical trial: comparison between off-site and on-site measurements. Clin Radiol 58: 311–314 - PubMed
    1. Boger-Megiddo I, Apter S, Spencer JA, Ben-Yehuda D, Nof E, Libson E (2002) Is chest CT sufficient for follow-up of primary mediastinal B-cell lymphoma in remission? Am J Roentgenol 178: 165–167 - PubMed
    1. Brix G, Nagel HD, Stamm G, Veit R, Lechel U, Griebel J, Galanski M (2003) Radiation exposure in multi-slice versus single-slice spiral CT: results of a nationwide survey. Eur Radiol 13: 1979–1991 - PubMed
    1. Brown AL, Middleton G, MacVicar AD, Husband JES (1998) T1-weighted magnetic resonance imaging in breast cancer vertebral metastases: changes on treatment and correlation with response to therapy. Clin Radiol 53: 493–501 - PubMed
    1. Carlson K, Åström G, Nyman R, Ahlstrom H, Simonsson B (1995) MR imaging of multiple myeloma in tumour mass measurement at diagnosis and during treatment. Acta Radiol 36: 9–14 - PubMed

Publication types

MeSH terms

LinkOut - more resources