Genetic structure of the purebred domestic dog - PubMed (original) (raw)
. 2004 May 21;304(5674):1160-4.
doi: 10.1126/science.1097406.
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- PMID: 15155949
- DOI: 10.1126/science.1097406
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Genetic structure of the purebred domestic dog
Heidi G Parker et al. Science. 2004.
Free article
Abstract
We used molecular markers to study genetic relationships in a diverse collection of 85 domestic dog breeds. Differences among breeds accounted for approximately 30% of genetic variation. Microsatellite genotypes were used to correctly assign 99% of individual dogs to breeds. Phylogenetic analysis separated several breeds with ancient origins from the remaining breeds with modern European origins. We identified four genetic clusters, which predominantly contained breeds with similar geographic origin, morphology, or role in human activities. These results provide a genetic classification of dog breeds and will aid studies of the genetics of phenotypic breed differences.
Comment in
- Genetics. Genome resources to boost canines' role in gene hunts.
Pennisi E. Pennisi E. Science. 2004 May 21;304(5674):1093-5. doi: 10.1126/science.304.5674.1093a. Science. 2004. PMID: 15155921 No abstract available.
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