Cranberry juice and urinary tract infection - PubMed (original) (raw)
Review
. 2004 May 15;38(10):1413-9.
doi: 10.1086/386328. Epub 2004 Apr 26.
Affiliations
- PMID: 15156480
- DOI: 10.1086/386328
Review
Cranberry juice and urinary tract infection
R Raz et al. Clin Infect Dis. 2004.
Abstract
Cranberries have long been the focus of interest for their beneficial effects in preventing urinary tract infections (UTIs). Cranberries contain 2 compounds with antiadherence properties that prevent fimbriated Escherichia coli from adhering to uroepithelial cells in the urinary tract. Approximately 1 dozen clinical trials have been performed testing the effects of cranberries on the urinary tract. However, these trials suffer from a number of limitations. Most importantly, the trials have used a wide variety of cranberry products, such as cranberry juice concentrate, cranberry juice cocktail, and cranberry capsules, and they have used different dosing regimens. Further research is required to clarify unanswered questions regarding the role of cranberries in protecting against UTI in general and in women with anatomical abnormalities in particular.
Comment in
- Antimicrobial mechanisms of cranberry juice.
Rhee KY, Charles M. Rhee KY, et al. Clin Infect Dis. 2004 Sep 15;39(6):877. doi: 10.1086/423278. Clin Infect Dis. 2004. PMID: 15472831 No abstract available. - Cranberry juice and urinary tract infection.
Schaeffer AJ. Schaeffer AJ. J Urol. 2005 Jan;173(1):111-2. doi: 10.1016/s0022-5347(05)60790-2. J Urol. 2005. PMID: 15592047 No abstract available.
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