Deletion of the Escherichia coli O14:K7 O antigen gene cluster - PubMed (original) (raw)
. 2004 Apr;50(4):299-302.
doi: 10.1139/w04-010.
Affiliations
- PMID: 15213754
- DOI: 10.1139/w04-010
Deletion of the Escherichia coli O14:K7 O antigen gene cluster
Slade O Jensen et al. Can J Microbiol. 2004 Apr.
Abstract
Escherichia coli O14:K7 is a rough strain, lacking a typical O antigen, in which the enterobacterial common antigen is attached to the lipopolysaccharide core. The rough phenotype was previously mapped to the O antigen gene cluster; however, the nature of the nonfunctional locus was not defined. In this study, we have shown that the O antigen gene cluster of an O14:K7 type strain (Su4411/41) was most likely deleted via homologous recombination between the GDP-mannose pathway genes (manB and manC) of the colanic acid and O antigen gene clusters. A similar recombination event has previously been inferred for the deletion of E. coli Sonnei chromosomal O antigen genes. Therefore, recombination between the GDP-mannose pathway genes provides a convenient mechanism for the deletion of O antigen genes, which may occur if the typical O antigen becomes redundant.
Similar articles
- [Sequence of Escherichia coli O141 O-antigen gene cluster and analyses of its evolutionary history].
Kong QK, Guo HJ, Zhao G, Guo X, Cheng JS, Wang L. Kong QK, et al. Yi Chuan Xue Bao. 2004 Dec;31(12):1448-54. Yi Chuan Xue Bao. 2004. PMID: 15633653 Chinese. - Genetic characterization of the Escherichia coli O66 antigen and functional identification of its wzy gene.
Cheng J, Liu B, Bastin DA, Han W, Wang L, Feng L. Cheng J, et al. J Microbiol. 2007 Feb;45(1):69-74. J Microbiol. 2007. PMID: 17342059 - Characterization of the Escherichia coli O59 and O155 O-antigen gene clusters: the atypical wzx genes are evolutionary related.
Guo H, Kong Q, Cheng J, Wang L, Feng L. Guo H, et al. FEMS Microbiol Lett. 2005 Jul 15;248(2):153-61. doi: 10.1016/j.femsle.2005.05.036. FEMS Microbiol Lett. 2005. PMID: 15990253 - 2F3 monoclonal antibody recognizes the O26 O-antigen moiety of the lipopolysaccharide of enterohemorrhagic Escherichia coli strain 4276.
Szalo IM, Taminiau B, Goffaux F, Pirson V, McCappin J, Ball HJ, Mainil JG. Szalo IM, et al. Clin Diagn Lab Immunol. 2004 May;11(3):532-7. doi: 10.1128/CDLI.11.3.532-537.2004. Clin Diagn Lab Immunol. 2004. PMID: 15138178 Free PMC article. - Molecular evolution of the GDP-mannose pathway genes (manB and manC) in Salmonella enterica.
Jensen SO, Reeves PR. Jensen SO, et al. Microbiology (Reading). 2001 Mar;147(Pt 3):599-610. doi: 10.1099/00221287-147-3-599. Microbiology (Reading). 2001. PMID: 11238967
Cited by
- A complete view of the genetic diversity of the Escherichia coli O-antigen biosynthesis gene cluster.
Iguchi A, Iyoda S, Kikuchi T, Ogura Y, Katsura K, Ohnishi M, Hayashi T, Thomson NR. Iguchi A, et al. DNA Res. 2015 Feb;22(1):101-7. doi: 10.1093/dnares/dsu043. Epub 2014 Nov 26. DNA Res. 2015. PMID: 25428893 Free PMC article. - Comparison of O-Antigen Gene Clusters of All O-Serogroups of Escherichia coli and Proposal for Adopting a New Nomenclature for O-Typing.
DebRoy C, Fratamico PM, Yan X, Baranzoni G, Liu Y, Needleman DS, Tebbs R, O'Connell CD, Allred A, Swimley M, Mwangi M, Kapur V, Raygoza Garay JA, Roberts EL, Katani R. DebRoy C, et al. PLoS One. 2016 Jan 29;11(1):e0147434. doi: 10.1371/journal.pone.0147434. eCollection 2016. PLoS One. 2016. PMID: 26824864 Free PMC article. - Interplay of the Wzx translocase and the corresponding polymerase and chain length regulator proteins in the translocation and periplasmic assembly of lipopolysaccharide o antigen.
Marolda CL, Tatar LD, Alaimo C, Aebi M, Valvano MA. Marolda CL, et al. J Bacteriol. 2006 Jul;188(14):5124-35. doi: 10.1128/JB.00461-06. J Bacteriol. 2006. PMID: 16816184 Free PMC article. - Resistance determinants and mobile genetic elements of an NDM-1-encoding Klebsiella pneumoniae strain.
Hudson CM, Bent ZW, Meagher RJ, Williams KP. Hudson CM, et al. PLoS One. 2014 Jun 6;9(6):e99209. doi: 10.1371/journal.pone.0099209. eCollection 2014. PLoS One. 2014. PMID: 24905728 Free PMC article. - Lipopolysaccharide-Linked Enterobacterial Common Antigen (ECALPS) Occurs in Rough Strains of Escherichia coli R1, R2, and R4.
Maciejewska A, Kaszowska M, Jachymek W, Lugowski C, Lukasiewicz J. Maciejewska A, et al. Int J Mol Sci. 2020 Aug 21;21(17):6038. doi: 10.3390/ijms21176038. Int J Mol Sci. 2020. PMID: 32839412 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous