Sites of neocortical reorganization critical for remote spatial memory - PubMed (original) (raw)

. 2004 Jul 2;305(5680):96-9.

doi: 10.1126/science.1098180.

Affiliations

• PMID: 15232109
• DOI: 10.1126/science.1098180

Sites of neocortical reorganization critical for remote spatial memory

Thibault Maviel et al. Science. 2004.

Erratum in

• Science. 2004 Aug 13;305(5686):946

Abstract

The hippocampus is crucial for spatial memory formation, yet it does not store long-lasting memories. By combining functional brain imaging and region-specific neuronal inactivation in mice, we identified prefrontal and anterior cingulate cortices as critical for storage and retrieval of remote spatial memories [correction]. Imaging of activity-dependent genes also revealed an involvement of parietal and retrosplenial cortices during consolidation of remote memory. Long-term memory storage within some of these neocortical regions was accompanied by structural changes including synaptogenesis and laminar reorganization, concomitant with a functional disengagement of the hippocampus and posterior cingulate cortex [correction]. Thus, consolidation of spatial memory requires a time-dependent hippocampal-cortical dialogue, ultimately enabling widespread cortical networks to mediate effortful recall and use of cortically stored remote memories independently.

PubMed Disclaimer

Similar articles

• New circuits for old memories: the role of the neocortex in consolidation.
  Wiltgen BJ, Brown RA, Talton LE, Silva AJ. Wiltgen BJ, et al. Neuron. 2004 Sep 30;44(1):101-8. doi: 10.1016/j.neuron.2004.09.015. Neuron. 2004. PMID: 15450163 Review.
• The involvement of the anterior cingulate cortex in remote contextual fear memory.
  Frankland PW, Bontempi B, Talton LE, Kaczmarek L, Silva AJ. Frankland PW, et al. Science. 2004 May 7;304(5672):881-3. doi: 10.1126/science.1094804. Science. 2004. PMID: 15131309
• A temporoparietal and prefrontal network for retrieving the spatial context of lifelike events.
  Burgess N, Maguire EA, Spiers HJ, O'Keefe J. Burgess N, et al. Neuroimage. 2001 Aug;14(2):439-53. doi: 10.1006/nimg.2001.0806. Neuroimage. 2001. PMID: 11467917
• Coordinated reactivation of distributed memory traces in primate neocortex.
  Hoffman KL, McNaughton BL. Hoffman KL, et al. Science. 2002 Sep 20;297(5589):2070-3. doi: 10.1126/science.1073538. Science. 2002. PMID: 12242447
• The organization of recent and remote memories.
  Frankland PW, Bontempi B. Frankland PW, et al. Nat Rev Neurosci. 2005 Feb;6(2):119-30. doi: 10.1038/nrn1607. Nat Rev Neurosci. 2005. PMID: 15685217 Review.

Cited by

• Noradrenergic signaling mediates cortical early tagging and storage of remote memory.
  Fan X, Song J, Ma C, Lv Y, Wang F, Ma L, Liu X. Fan X, et al. Nat Commun. 2022 Dec 9;13(1):7623. doi: 10.1038/s41467-022-35342-x. Nat Commun. 2022. PMID: 36494350 Free PMC article.
• Topography of Arc/Arg3.1 mRNA expression in the dorsal and ventral hippocampus induced by recent and remote spatial memory recall: dissociation of CA3 and CA1 activation.
  Gusev PA, Cui C, Alkon DL, Gubin AN. Gusev PA, et al. J Neurosci. 2005 Oct 12;25(41):9384-97. doi: 10.1523/JNEUROSCI.0832-05.2005. J Neurosci. 2005. PMID: 16221847 Free PMC article.
• Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.
  de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, Biederer T. de Arce KP, et al. Nat Commun. 2023 Jan 28;14(1):459. doi: 10.1038/s41467-023-36042-w. Nat Commun. 2023. PMID: 36709330 Free PMC article.
• Adaptive Immune Deficiency Impairs Neural Activity After Training and Retrieval.
  Li H, Fu Z, Hu M, Xu X. Li H, et al. Front Neurosci. 2021 Nov 15;15:739580. doi: 10.3389/fnins.2021.739580. eCollection 2021. Front Neurosci. 2021. PMID: 34867154 Free PMC article.
• Impaired long-term stability of CA1 place cell representation in mice lacking the transcription factor zif268/egr1.
  Renaudineau S, Poucet B, Laroche S, Davis S, Save E. Renaudineau S, et al. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11771-5. doi: 10.1073/pnas.0900484106. Epub 2009 Jun 25. Proc Natl Acad Sci U S A. 2009. PMID: 19556537 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Atypon
  • Ovid Technologies, Inc.

• Other Literature Sources

  • H1 Connect

• Medical

  • MedlinePlus Health Information