Cancer immunotherapy: a treatment for the masses - PubMed (original) (raw)
Review
. 2004 Jul 9;305(5681):200-5.
doi: 10.1126/science.1100369.
Affiliations
- PMID: 15247469
- DOI: 10.1126/science.1100369
Review
Cancer immunotherapy: a treatment for the masses
Joseph N Blattman et al. Science. 2004.
Abstract
Cancer immunotherapy attempts to harness the exquisite power and specificity of the immune system for the treatment of malignancy. Although cancer cells are less immunogenic than pathogens, the immune system is clearly capable of recognizing and eliminating tumor cells. However, tumors frequently interfere with the development and function of immune responses. Thus, the challenge for immunotherapy is to use advances in cellular and molecular immunology to develop strategies that effectively and safely augment antitumor responses.
Similar articles
- Cancer immunogene therapy.
Yoshizawa H, Kagamu H, Gejyo F. Yoshizawa H, et al. Arch Immunol Ther Exp (Warsz). 2001;49(5):337-43. Arch Immunol Ther Exp (Warsz). 2001. PMID: 11798131 Review. - Tumor vaccine: current trends in antigen specific immunotherapy.
Baral R. Baral R. Indian J Exp Biol. 2005 May;43(5):389-406. Indian J Exp Biol. 2005. PMID: 15900903 Review. - Exploiting dendritic cells and natural killer T cells in immunotherapy against malignancies.
Fujii S. Fujii S. Trends Immunol. 2008 May;29(5):242-9. doi: 10.1016/j.it.2008.02.002. Epub 2008 Mar 26. Trends Immunol. 2008. PMID: 18372215 Review. - Tumor immunity and immunotherapy.
Boura P, Kountouras J, Lygidakis NJ. Boura P, et al. Hepatogastroenterology. 2001 Jul-Aug;48(40):1040-4. Hepatogastroenterology. 2001. PMID: 11490795 Review. - Cellular and humoral immune responses of cancer patients to defined tumor antigens.
Jäger D, Jäger E, Bert F, Knuth A. Jäger D, et al. Cancer Chemother Biol Response Modif. 2001;19:385-93. Cancer Chemother Biol Response Modif. 2001. PMID: 11686025 Review. No abstract available.
Cited by
- Immunomodulation of human T cells by microbubble-mediated focused ultrasound.
Baez A, Singh D, He S, Hajiaghayi M, Gholizadeh F, Darlington PJ, Helfield B. Baez A, et al. Front Immunol. 2024 Oct 22;15:1486744. doi: 10.3389/fimmu.2024.1486744. eCollection 2024. Front Immunol. 2024. PMID: 39502696 Free PMC article. - Peripheral blood CD40-CD40L expression in human breast cancer.
Pan W, Gong J, Yang C, Feng R, Guo F, Sun Y, Chen H. Pan W, et al. Ir J Med Sci. 2013 Dec;182(4):719-21. doi: 10.1007/s11845-013-0931-0. Epub 2013 Feb 28. Ir J Med Sci. 2013. PMID: 23456134 - The in vivo expansion rate of properly stimulated transferred CD8+ T cells exceeds that of an aggressively growing mouse tumor.
Hwang LN, Yu Z, Palmer DC, Restifo NP. Hwang LN, et al. Cancer Res. 2006 Jan 15;66(2):1132-8. doi: 10.1158/0008-5472.CAN-05-1679. Cancer Res. 2006. PMID: 16424050 Free PMC article. - Analysis of adenovirus trans-complementation-mediated gene expression controlled by melanoma-specific TETP promoter in vitro.
Fontecedro AC, Lutschg V, Eichhoff O, Dummer R, Greber UF, Hemmi S. Fontecedro AC, et al. Virol J. 2010 Jul 29;7:175. doi: 10.1186/1743-422X-7-175. Virol J. 2010. PMID: 20670430 Free PMC article. - Application of injectable hydrogels in cancer immunotherapy.
Liu C, Liao Y, Liu L, Xie L, Liu J, Zhang Y, Li Y. Liu C, et al. Front Bioeng Biotechnol. 2023 Feb 3;11:1121887. doi: 10.3389/fbioe.2023.1121887. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 36815890 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources