Bilirubin: an endogenous product of heme degradation with both cytotoxic and cytoprotective properties - PubMed (original) (raw)
Review
Bilirubin: an endogenous product of heme degradation with both cytotoxic and cytoprotective properties
Jaime Kapitulnik. Mol Pharmacol. 2004 Oct.
No abstract available
Similar articles
- New physiological importance of two classic residual products: carbon monoxide and bilirubin.
Marilena G. Marilena G. Biochem Mol Med. 1997 Aug;61(2):136-42. doi: 10.1006/bmme.1997.2610. Biochem Mol Med. 1997. PMID: 9259978 Review. - Bilirubin inhibits iNOS expression and NO production in response to endotoxin in rats.
Wang WW, Smith DL, Zucker SD. Wang WW, et al. Hepatology. 2004 Aug;40(2):424-33. doi: 10.1002/hep.20334. Hepatology. 2004. PMID: 15368447 - Overview of heme degradation pathway.
Maines MD. Maines MD. Curr Protoc Toxicol. 2001 May;Chapter 9:Unit 9.1. doi: 10.1002/0471140856.tx0901s00. Curr Protoc Toxicol. 2001. PMID: 23045067 Review. - Bilirubin and glutathione have complementary antioxidant and cytoprotective roles.
Sedlak TW, Saleh M, Higginson DS, Paul BD, Juluri KR, Snyder SH. Sedlak TW, et al. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5171-6. doi: 10.1073/pnas.0813132106. Epub 2009 Mar 13. Proc Natl Acad Sci U S A. 2009. PMID: 19286972 Free PMC article. - Detection of heme oxygenase 1 and 2 proteins and bilirubin formation.
McCoubrey WK Jr. McCoubrey WK Jr. Curr Protoc Toxicol. 2001 May;Chapter 9:Unit 9.3. doi: 10.1002/0471140856.tx0903s00. Curr Protoc Toxicol. 2001. PMID: 23045069
Cited by
- Developmental onset of bilirubin-induced neurotoxicity involves Toll-like receptor 2-dependent signaling in humanized UDP-glucuronosyltransferase1 mice.
Yueh MF, Chen S, Nguyen N, Tukey RH. Yueh MF, et al. J Biol Chem. 2014 Feb 21;289(8):4699-709. doi: 10.1074/jbc.M113.518613. Epub 2014 Jan 8. J Biol Chem. 2014. PMID: 24403077 Free PMC article. - Intermittent hypoxia simulating obstructive sleep apnea causes pulmonary inflammation and activates the Nrf2/HO-1 pathway.
Wang Y, Chai Y, He X, Ai L, Sun X, Huang Y, Li Y. Wang Y, et al. Exp Ther Med. 2017 Oct;14(4):3463-3470. doi: 10.3892/etm.2017.4971. Epub 2017 Aug 18. Exp Ther Med. 2017. PMID: 29042934 Free PMC article. - Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation.
Fattori V, Pinho-Ribeiro FA, Borghi SM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA Jr. Fattori V, et al. Inflamm Res. 2015 Dec;64(12):993-1003. doi: 10.1007/s00011-015-0885-y. Epub 2015 Oct 11. Inflamm Res. 2015. PMID: 26456836 - Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice.
Wang LF, Yokoyama KK, Lin CL, Chen TY, Hsiao HW, Chiang PC, Hsu C. Wang LF, et al. Sci Rep. 2016 May 20;6:26358. doi: 10.1038/srep26358. Sci Rep. 2016. PMID: 27198537 Free PMC article.