Peptide selection by class I molecules of the major histocompatibility complex - PubMed (original) (raw)
Peptide selection by class I molecules of the major histocompatibility complex
T Elliott et al. Curr Biol. 1993.
Abstract
Class I molecules of the major histocompatibility complex (MHC) bind peptides derived from cytoplasmic proteins. Comparison of over 100 such peptides reveals the importance of the carboxy-terminal residue in selective binding. Recent evidence implicates the proteases and transporters of the processing pathway in providing peptides with the correct residues at the carboxyl terminus.
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