Position paper: cathartics - PubMed (original) (raw)
Review
Position paper: cathartics
No authors listed. J Toxicol Clin Toxicol. 2004.
Erratum in
- J Toxicol Clin Toxicol. 2004;42(7):1000
Abstract
The administration of a cathartic alone has no role in the management of the poisoned patient and is not recommended as a method of gut decontamination. Experimental data are conflicting regarding the use of cathartics in combination with activated charcoal. No clinical studies have been published to investigate the ability of a cathartic, with or without activated charcoal, to reduce the bioavailability of drugs or to improve the outcome of poisoned patients. Based on available data, the routine use of a cathartic in combination with activated charcoal is not endorsed. If a cathartic is used, it should be limited to a single dose in order to minimize adverse effects of the cathartic. A review of the literature since the preparation of the 1997 Cathartics Position Statement revealed no new evidence that would require a revision of the conclusions of the Statement.
Comment in
- The revised position papers on gastric decontamination.
Buckley NA, Eddleston M. Buckley NA, et al. Clin Toxicol (Phila). 2005;43(2):129-30. doi: 10.1081/clt-200050420. Clin Toxicol (Phila). 2005. PMID: 15822769 Free PMC article. No abstract available.
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