Clinical differentiation of parkinsonian syndromes: prognostic and therapeutic relevance - PubMed (original) (raw)
Review
Clinical differentiation of parkinsonian syndromes: prognostic and therapeutic relevance
Chadwick W Christine et al. Am J Med. 2004.
Abstract
Parkinson disease is the most common cause of parkinsonism, but other causes should always be excluded because they have a different prognosis, respond differently to medical treatment, and should not be managed by surgical means. However, diagnosis, even by experts, is challenging; one autopsy series showed an error rate of 24%. Distinction between various diagnostic possibilities depends on the history and examination findings. The use of certain medications, the rapid rate of disease progression, early onset of falling, the presence of certain dysautonomic symptoms, cognitive or behavioral changes, or a history of poor response to dopaminergic therapy may suggest an atypical form of parkinsonism. Postural hypotension, dementia, supranuclear ophthalmoparesis, or early postural instability should alert the examiner to consider an atypical cause of parkinsonism. Tests of autonomic function and brain imaging are often helpful in distinguishing these diseases.
Copyright 2004 Elsevier Inc.
Similar articles
- [Atypical Parkinson syndromes--recent advances in diagnosis and therapy].
Duerr S, Wenning GK, Seppi K, Poewe W. Duerr S, et al. Fortschr Neurol Psychiatr. 2012 Sep;80(9):492-500. doi: 10.1055/s-0031-1299349. Epub 2012 Mar 28. Fortschr Neurol Psychiatr. 2012. PMID: 22457226 Review. German. - Caribbean parkinsonism and other atypical parkinsonian disorders.
Tolosa E, Calandrella D, Gallardo M. Tolosa E, et al. Parkinsonism Relat Disord. 2004 May;10 Suppl 1:S19-26. doi: 10.1016/j.parkreldis.2004.02.003. Parkinsonism Relat Disord. 2004. PMID: 15109583 Review. - [Diagnostic criteria of parkinsonian syndromes].
Tison F. Tison F. Rev Neurol (Paris). 2003 May;159(5 Pt 2):3S19-23. Rev Neurol (Paris). 2003. PMID: 12773884 French. - [Atypical parkinsonism].
Tysnes OB, Vilming ST. Tysnes OB, et al. Tidsskr Nor Laegeforen. 2008 Sep 25;128(18):2077-80. Tidsskr Nor Laegeforen. 2008. PMID: 18846125 Review. Norwegian. - [What is typical in atypical Parkinsonian syndromes?].
Wallesch CW. Wallesch CW. Fortschr Neurol Psychiatr. 2012 Sep;80(9):491. doi: 10.1055/s-0032-1313103. Epub 2012 Sep 5. Fortschr Neurol Psychiatr. 2012. PMID: 22951770 German. No abstract available.
Cited by
- Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
He D, Liu Y, Li J, Wang H, Ye B, He Y, Li Z, Gao X, Fu S, Liu D. He D, et al. Cells. 2022 Sep 19;11(18):2927. doi: 10.3390/cells11182927. Cells. 2022. PMID: 36139502 Free PMC article. - Trimetazidine Use and the Risk of Parkinsonism: A Nationwide Population-Based Study.
Kim S, Yu YM, Kwon J, Jeong KH, Lee JS, Lee E. Kim S, et al. Int J Environ Res Public Health. 2020 Oct 4;17(19):7256. doi: 10.3390/ijerph17197256. Int J Environ Res Public Health. 2020. PMID: 33020406 Free PMC article. - Distribution of non-motor symptoms in idiopathic Parkinson's disease and secondary Parkinsonism.
Skogar O, Nilsson M. Skogar O, et al. J Multidiscip Healthc. 2018 Oct 4;11:525-534. doi: 10.2147/JMDH.S170307. eCollection 2018. J Multidiscip Healthc. 2018. PMID: 30323614 Free PMC article. - Hydrothermal Synthesis of Nitrogen-Doped Carbon Quantum Dots as Fluorescent Probes for the Detection of Dopamine.
Zhao C, Jiao Y, Hua J, Yang J, Yang Y. Zhao C, et al. J Fluoresc. 2018 Jan;28(1):269-276. doi: 10.1007/s10895-017-2189-9. Epub 2017 Nov 7. J Fluoresc. 2018. PMID: 29116607 - Family Functioning and Communication in Spouses of Patients with Parkinsonism.
Kang SY, Yang MH, Lee JA, Jang W, Lee CS, Kim YS. Kang SY, et al. Korean J Fam Med. 2017 Jan;38(1):14-20. doi: 10.4082/kjfm.2017.38.1.14. Epub 2017 Jan 18. Korean J Fam Med. 2017. PMID: 28197328 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources