Crisscross regulation of cell-type-specific gene expression during development in B. subtilis - PubMed (original) (raw)
Review
. 1992 Feb 13;355(6361):601-4.
doi: 10.1038/355601a0.
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- PMID: 1538747
- DOI: 10.1038/355601a0
Review
Crisscross regulation of cell-type-specific gene expression during development in B. subtilis
R Losick et al. Nature. 1992.
Abstract
Sporulation in Bacillus subtilis is a model for how cells of one type generate other differentiated cell types. During sporulation two cellular compartments arise that differ from each other and from the progenitor cell. Differential gene expression between the two is governed by the successive appearance of four transcription factors whose activities are coordinated in crisscross fashion between the two cells.
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