Endocannabinoids and exercise - PubMed (original) (raw)
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Endocannabinoids and exercise
A Dietrich et al. Br J Sports Med. 2004 Oct.
Abstract
Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes. This article provides an overview of this emerging field.
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References
- Neurosci Lett. 1998 May 1;246(3):169-72 - PubMed
- Pharmacol Biochem Behav. 1991 Nov;40(3):571-80 - PubMed
- Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10269-73 - PubMed
- J Neurosci. 1994 Jun;14(6):3775-90 - PubMed
- Brain Cogn. 2004 Aug;55(3):516-24 - PubMed