Restless legs syndrome and pregnancy - PubMed (original) (raw)
Restless legs syndrome and pregnancy
M Manconi et al. Neurology. 2004.
Abstract
Objective: To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy and the puerperium.
Methods: A structured clinical interview, assessing symptoms since the beginning of pregnancy, was performed to a population of 642 pregnant women at the time of delivery and at follow-up evaluation (1, 3, and 6 months after delivery). Main hematologic tests were also evaluated. A woman was considered affected if she met the International RLS Study Group criteria for RLS diagnosis.
Results: Twenty-six percent of women were affected by RLS during their pregnancy. The disease was strongly related to the third trimester of pregnancy and tended to disappear reaching the time of delivery. Affected women presented lower values of hemoglobin and mean corpuscular volume compared with healthy subjects (both groups received the same supplemental iron and folate therapy).
Conclusions: Pregnancy is associated with transient restless legs syndrome.
Similar articles
- Restless legs syndrome among pregnant women in China: prevalence and risk factors.
Shang X, Yang J, Guo Y, Ma S, Jia Z, Xue R. Shang X, et al. Sleep Breath. 2015 Sep;19(3):1093-9. doi: 10.1007/s11325-014-1089-3. Epub 2014 Dec 2. Sleep Breath. 2015. PMID: 25450154 - Characteristics and determinants of restless legs syndrome in pregnancy: a prospective study.
Hübner A, Krafft A, Gadient S, Werth E, Zimmermann R, Bassetti CL. Hübner A, et al. Neurology. 2013 Feb 19;80(8):738-42. doi: 10.1212/WNL.0b013e318283baf3. Epub 2013 Feb 6. Neurology. 2013. PMID: 23390174 - Prevalence and risk factors for restless legs syndrome during pregnancy in a Northern Italian population.
Esposito G, Odelli V, Romiti L, Chiaffarino F, Di Martino M, Ricci E, Mauri PA, Bulfoni A, Parazzini F. Esposito G, et al. J Obstet Gynaecol. 2019 May;39(4):480-484. doi: 10.1080/01443615.2018.1525341. Epub 2019 Jan 8. J Obstet Gynaecol. 2019. PMID: 30620232 - When gender matters: restless legs syndrome. Report of the "RLS and woman" workshop endorsed by the European RLS Study Group.
Manconi M, Ulfberg J, Berger K, Ghorayeb I, Wesström J, Fulda S, Allen RP, Pollmächer T. Manconi M, et al. Sleep Med Rev. 2012 Aug;16(4):297-307. doi: 10.1016/j.smrv.2011.08.006. Epub 2011 Nov 9. Sleep Med Rev. 2012. PMID: 22075215 Review. - Restless legs syndrome and pregnancy: a review.
Srivanitchapoom P, Pandey S, Hallett M. Srivanitchapoom P, et al. Parkinsonism Relat Disord. 2014 Jul;20(7):716-22. doi: 10.1016/j.parkreldis.2014.03.027. Epub 2014 Apr 8. Parkinsonism Relat Disord. 2014. PMID: 24768121 Free PMC article. Review.
Cited by
- Prevalence of the restless legs syndrome in transsexual patients: the hormonal hypothesis revisited.
Fulda S, Stalla GK, Wetter TC. Fulda S, et al. J Neurol. 2007 Dec;254(12):1748-9. doi: 10.1007/s00415-007-0624-6. Epub 2007 Nov 9. J Neurol. 2007. PMID: 17990060 No abstract available. - [Analysis of causes or reasons that fragment sleep and sleep disorder in pregnant and non-pregnant women].
Valiensi SM, Izbizky GH. Valiensi SM, et al. Rev Fac Cien Med Univ Nac Cordoba. 2022 Dec 21;79(4):318-326. doi: 10.31053/1853.0605.v79.n4.31046. Rev Fac Cien Med Univ Nac Cordoba. 2022. PMID: 36542590 Free PMC article. Spanish. - The Prevalence, Severity, and Predictive Factors of Restless Legs Syndrome in Pregnancy.
Turan H, Aşkın Turan S, Butun Z, Kayapınar M. Turan H, et al. Cureus. 2023 Sep 8;15(9):e44884. doi: 10.7759/cureus.44884. eCollection 2023 Sep. Cureus. 2023. PMID: 37692184 Free PMC article. - Gabapentin enacarbil for the treatment of moderate to severe primary restless legs syndrome (Willis-Ekbom disease): 600 or 1,200 mg dose?
Kume A. Kume A. Neuropsychiatr Dis Treat. 2014 Feb 3;10:249-62. doi: 10.2147/NDT.S30160. eCollection 2014. Neuropsychiatr Dis Treat. 2014. PMID: 24523590 Free PMC article. Review. - Restless legs syndrome and hypertension in Chinese pregnant women.
Ma S, Shang X, Guo Y, Liu G, Yang J, Xue R. Ma S, et al. Neurol Sci. 2015 Jun;36(6):877-81. doi: 10.1007/s10072-015-2094-4. Epub 2015 Feb 3. Neurol Sci. 2015. PMID: 25647293
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous