Mannheim intima-media thickness consensus - PubMed (original) (raw)
Review
doi: 10.1159/000081812. Epub 2004 Nov 2.
M G Hennerici, S Meairs, H Adams, P Amarenco, M Desvarieux, S Ebrahim, M Fatar, R Hernandez Hernandez, S Kownator, P Prati, T Rundek, A Taylor, N Bornstein, L Csiba, E Vicaut, K S Woo, F Zannad; Advisory Board of the 3rd Watching the Risk Symposium 2004, 13th European Stroke Conference
- PMID: 15523176
- DOI: 10.1159/000081812
Review
Mannheim intima-media thickness consensus
P-J Touboul et al. Cerebrovasc Dis. 2004.
Abstract
Intima-media thickness (IMT) is increasingly used in clinical trials as a surrogate end point for determining the success of interventions that lower risk factors for atherosclerosis. The necessity for unified criteria to distinguish early atherosclerotic plaque formation from thickening of IMT and to standardize IMT measurements is addressed in this consensus statement. Plaque is defined as a focal structure that encroaches into the arterial lumen of at least 0.5 mm or 50% of the surrounding IMT value or demonstrates a thickness of > or =1.5 mm as measured from the media-adventitia interface to the intima-lumen interface. Standard use of IMT measurements is recommended in all epidemiological and interventional trials dealing with vascular diseases to improve characterization of the population investigated. The consensus concludes that there is no need to 'treat IMT values' nor to monitor IMT values in individual patients apart from few exceptions. Although IMT has been suggested to represent an important risk marker, it does not fulfill the characteristics of an accepted risk factor. Standardized methods recommended in this consensus statement will foster homogenous data collection and analysis. This will help to improve the power of studies incorporating IMT measurements and to facilitate the merging of large databases for meta-analyses.
Comment in
- Mannheim consensus on carotid intima-media thickness: opposite and complementary points of view.
Meijer R, Grobee DE, Bots ML. Meijer R, et al. Cerebrovasc Dis. 2006;21(5-6):415-6. doi: 10.1159/000092129. Epub 2006 Mar 20. Cerebrovasc Dis. 2006. PMID: 16549909 No abstract available.
Similar articles
- Mannheim carotid intima-media thickness consensus (2004-2006). An update on behalf of the Advisory Board of the 3rd and 4th Watching the Risk Symposium, 13th and 15th European Stroke Conferences, Mannheim, Germany, 2004, and Brussels, Belgium, 2006.
Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, Csiba L, Desvarieux M, Ebrahim S, Fatar M, Hernandez Hernandez R, Jaff M, Kownator S, Prati P, Rundek T, Sitzer M, Schminke U, Tardif JC, Taylor A, Vicaut E, Woo KS, Zannad F, Zureik M. Touboul PJ, et al. Cerebrovasc Dis. 2007;23(1):75-80. doi: 10.1159/000097034. Epub 2006 Nov 14. Cerebrovasc Dis. 2007. PMID: 17108679 - Mannheim carotid intima-media thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011.
Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, Csiba L, Desvarieux M, Ebrahim S, Hernandez Hernandez R, Jaff M, Kownator S, Naqvi T, Prati P, Rundek T, Sitzer M, Schminke U, Tardif JC, Taylor A, Vicaut E, Woo KS. Touboul PJ, et al. Cerebrovasc Dis. 2012;34(4):290-6. doi: 10.1159/000343145. Epub 2012 Nov 1. Cerebrovasc Dis. 2012. PMID: 23128470 Free PMC article. - [Intima media thickness of the carotid arteries: early pointer to arteriosclerosis and therapeutic endpoint].
Ludwig M, von Petzinger-Kruthoff A, von Buquoy M, Stumpe KO. Ludwig M, et al. Ultraschall Med. 2003 Jun;24(3):162-74. doi: 10.1055/s-2003-40058. Ultraschall Med. 2003. PMID: 12817310 Review. German. - [Intima-media thickness in healthy probands without risk factors for arteriosclerosis].
Temelkova-Kurktschiev T, Fischer S, Koehler C, Mennicken G, Henkel E, Hanefeld M. Temelkova-Kurktschiev T, et al. Dtsch Med Wochenschr. 2001 Feb 23;126(8):193-7. doi: 10.1055/s-2001-11317. Dtsch Med Wochenschr. 2001. PMID: 11256022 German. - Reproducibility of in vivo carotid intima-media thickness measurements: a review.
Kanters SD, Algra A, van Leeuwen MS, Banga JD. Kanters SD, et al. Stroke. 1997 Mar;28(3):665-71. doi: 10.1161/01.str.28.3.665. Stroke. 1997. PMID: 9056629 Review.
Cited by
- Early-Life Risk Factors for Carotid Intima-Media Thickness and Carotid Stiffness in Adolescence.
van der Linden IA, Roodenburg R, Nijhof SL, van der Ent CK, Venekamp RP, van der Laan SEI, Schipper HS. van der Linden IA, et al. JAMA Netw Open. 2024 Sep 3;7(9):e2434699. doi: 10.1001/jamanetworkopen.2024.34699. JAMA Netw Open. 2024. PMID: 39302677 Free PMC article. - Adherence to a Healthy Diet and Risk of Multiple Carotid Atherosclerosis Subtypes: Insights from the China MJ Health Check-Up Cohort.
Fu J, Deng Y, Ma Y, Man S, Yang X, Yu C, Lv J, Liu H, Wang B, Li L. Fu J, et al. Nutrients. 2024 Jul 19;16(14):2338. doi: 10.3390/nu16142338. Nutrients. 2024. PMID: 39064782 Free PMC article. - Influence of nonalcoholic fatty liver disease severity on carotid adventitial vasa vasorum.
León-Mengíbar J, Sánchez E, Herrerías F, De La Fuente MC, Santamaría M, Valdivielso JM, Bermúdez-López M, Castro E, Pallarés J, Matias-Guiu X, Vilardell F, Caixàs A, Bueno M, Martí R, Lecube A. León-Mengíbar J, et al. Front Endocrinol (Lausanne). 2024 May 7;15:1366015. doi: 10.3389/fendo.2024.1366015. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38774226 Free PMC article. - Unlocking the Dietary Puzzle: How Macronutrient Intake Shapes the Relationship between Visfatin and Atherosclerosis in Type 2 Diabetes.
Kärberg K, Forbes A, Lember M. Kärberg K, et al. Medicina (Kaunas). 2024 Mar 6;60(3):438. doi: 10.3390/medicina60030438. Medicina (Kaunas). 2024. PMID: 38541164 Free PMC article. - National and Provincial-Level Prevalence and Risk Factors of Carotid Atherosclerosis in Chinese Adults.
Fu J, Deng Y, Ma Y, Man S, Yang X, Yu C, Lv J, Wang B, Li L. Fu J, et al. JAMA Netw Open. 2024 Jan 2;7(1):e2351225. doi: 10.1001/jamanetworkopen.2023.51225. JAMA Netw Open. 2024. PMID: 38206625 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources