Plasmacytoid dendritic cells in immunity - PubMed (original) (raw)

Review

. 2004 Dec;5(12):1219-26.

doi: 10.1038/ni1141.

Affiliations

• PMID: 15549123
• DOI: 10.1038/ni1141

Review

Plasmacytoid dendritic cells in immunity

Marco Colonna et al. Nat Immunol. 2004 Dec.

Abstract

Human and mouse plasmacytoid dendritic cells have been shown to correspond to a specialized cell population that produces large amounts of type I interferons in response to viruses, the so-called natural interferon-producing cells. As a result, intensive investigation is now focused on the potential functions of plasmacytoid dendritic cells in both innate and adaptive immunity. Here we review recent progress on the characterization of plasmacytoid dendritic cell origin, development, migration and function in immunity and tolerance, as well as their effect on human diseases.

PubMed Disclaimer

Similar articles

• From plasmacytoid to dendritic cell: morphological and functional switches during plasmacytoid pre-dendritic cell differentiation.
  Soumelis V, Liu YJ. Soumelis V, et al. Eur J Immunol. 2006 Sep;36(9):2286-92. doi: 10.1002/eji.200636026. Eur J Immunol. 2006. PMID: 16892183 Review.
• Plasmacytoid dendritic cells--virus experts of innate immunity.
  Barchet W, Cella M, Colonna M. Barchet W, et al. Semin Immunol. 2005 Aug;17(4):253-61. doi: 10.1016/j.smim.2005.05.008. Semin Immunol. 2005. PMID: 15990333 Review.
• Dendritic cells and the immunity/tolerance decision.
  Usharauli D. Usharauli D. Med Hypotheses. 2005;64(1):112-3. doi: 10.1016/j.mehy.2004.02.061. Med Hypotheses. 2005. PMID: 15533624
• Linking innate to adaptive immunity through dendritic cells.
  Steinman RM. Steinman RM. Novartis Found Symp. 2006;279:101-9; discussion 109-13, 216-9. Novartis Found Symp. 2006. PMID: 17278389 Review.

Cited by

• Preclinical Development of a Novel Zika Virus-like Particle Vaccine in Combination with Tetravalent Dengue Virus-like Particle Vaccines.
  Rothen DA, Dutta SK, Krenger PS, Pardini A, Vogt AS, Josi R, Lieknina I, Osterhaus ADME, Mohsen MO, Vogel M, Martina B, Tars K, Bachmann MF. Rothen DA, et al. Vaccines (Basel). 2024 Sep 14;12(9):1053. doi: 10.3390/vaccines12091053. Vaccines (Basel). 2024. PMID: 39340083 Free PMC article.
• Redefining our vision: an updated guide to the ocular immune system.
  Wu M, Fletcher EL, Chinnery HR, Downie LE, Mueller SN. Wu M, et al. Nat Rev Immunol. 2024 Aug 30. doi: 10.1038/s41577-024-01064-y. Online ahead of print. Nat Rev Immunol. 2024. PMID: 39215057 Review.
• Crucial role of dendritic cells in the generation of anti-tumor T-cell responses and immunogenic tumor microenvironment to suppress tumor development.
  Tominaga M, Uto T, Fukaya T, Mitoma S, Riethmacher D, Umekita K, Yamashita Y, Sato K. Tominaga M, et al. Front Immunol. 2024 Aug 14;15:1200461. doi: 10.3389/fimmu.2024.1200461. eCollection 2024. Front Immunol. 2024. PMID: 39206204 Free PMC article.
• Oncolytic virus and tumor-associated macrophage interactions in cancer immunotherapy.
  Lecoultre M, Walker PR, El Helali A. Lecoultre M, et al. Clin Exp Med. 2024 Aug 28;24(1):202. doi: 10.1007/s10238-024-01443-8. Clin Exp Med. 2024. PMID: 39196415 Free PMC article. Review.
• Molluscum Contagiosum Virus: Biology and Immune Response.
  Santacroce L, Magrone T. Santacroce L, et al. Adv Exp Med Biol. 2024;1451:151-170. doi: 10.1007/978-3-031-57165-7_10. Adv Exp Med Biol. 2024. PMID: 38801577 Review.

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • Nature Publishing Group

• Other Literature Sources

  • The Lens - Patent Citations

• Research Materials

  • NCI CPTC Antibody Characterization Program