Development of the nervus terminalis: origin and migration - PubMed (original) (raw)
Review
Development of the nervus terminalis: origin and migration
Kathleen E Whitlock. Microsc Res Tech. 2004 Sep.
Abstract
The origin of the nervus terminalis is one of the least well understood developmental events involved in generating the cranial ganglia of the forebrain in vertebrate animals. This cranial nerve forms at the formidable interface of the anteriormost limits of migrating cranial neural crest cells, the terminal end of the neural tube and the differentiating olfactory and adenohypophyseal placodes. The complex cellular interactions that give rise to the various structures associated with the sensory placode (olfactory) and endocrine placode (adenohypophysis) surround and engulf this enigmatic cranial nerve. The tortured history of nervus terminalis development (see von Bartheld, this issue, pages 13-24) reflects the lack of consensus on the origin (or origins), as well as the experimental difficulties in uncovering the origin, of the nervus terminalis. Recent technical advances have allowed us to make headway in understanding the origin(s) of this nerve. The emergence of the externally fertilized zebrafish embryo as a model system for developmental biology and genetics has shed new light on this century-old problem. Coupled with new developmental models are techniques that allow us to trace lineage, visualize gene expression, and genetically ablate cells, adding to our experimental tools with which to follow up on studies provided by our scientific predecessors. Through these techniques, a picture is emerging in which the origin of at least a subset of the nervus terminalis cells lies in the cranial neural crest. In this review, the data surrounding this finding will be discussed in light of recent findings on neural crest and placode origins.
Copyright 2004 Wiley-Liss, Inc.
Similar articles
- A new model for olfactory placode development.
Whitlock KE. Whitlock KE. Brain Behav Evol. 2004;64(3):126-40. doi: 10.1159/000079742. Brain Behav Evol. 2004. PMID: 15353905 Review. - Early development of the cranial sensory nervous system: from a common field to individual placodes.
Streit A. Streit A. Dev Biol. 2004 Dec 1;276(1):1-15. doi: 10.1016/j.ydbio.2004.08.037. Dev Biol. 2004. PMID: 15531360 Review. - Migration of neuroblasts from neurogenic placodes.
Begbie J. Begbie J. Dev Neurosci. 2008;30(1-3):33-5. doi: 10.1159/000109849. Dev Neurosci. 2008. PMID: 18075252 Review. - A role for foxd3 and sox10 in the differentiation of gonadotropin-releasing hormone (GnRH) cells in the zebrafish Danio rerio.
Whitlock KE, Smith KM, Kim H, Harden MV. Whitlock KE, et al. Development. 2005 Dec;132(24):5491-502. doi: 10.1242/dev.02158. Epub 2005 Nov 16. Development. 2005. PMID: 16291787 - Primary olfactory projections and the nervus terminalis in the African lungfish: implications for the phylogeny of cranial nerves.
von Bartheld CS, Claas B, Münz H, Meyer DL. von Bartheld CS, et al. Am J Anat. 1988 Aug;182(4):325-34. doi: 10.1002/aja.1001820404. Am J Anat. 1988. PMID: 2847523
Cited by
- Olfactory placode generates a diverse population of neurons expressing GnRH, somatostatin mRNA, neuropeptide Y, or calbindin in the chick forebrain.
Murakami S, Ohki-Hamazaki H, Uchiyama Y. Murakami S, et al. J Comp Neurol. 2022 Dec;530(17):2977-2993. doi: 10.1002/cne.25389. Epub 2022 Jul 17. J Comp Neurol. 2022. PMID: 35844047 Free PMC article. - The Olfactory Tract: Basis for Future Evolution in Response to Rapidly Changing Ecological Niches.
Whitlock KE, Palominos MF. Whitlock KE, et al. Front Neuroanat. 2022 Mar 3;16:831602. doi: 10.3389/fnana.2022.831602. eCollection 2022. Front Neuroanat. 2022. PMID: 35309251 Free PMC article. Review. - Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome.
Cho HJ, Shan Y, Whittington NC, Wray S. Cho HJ, et al. Front Cell Dev Biol. 2019 Jul 11;7:121. doi: 10.3389/fcell.2019.00121. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31355196 Free PMC article. - Neuroendocrinology of reproduction: Is gonadotropin-releasing hormone (GnRH) dispensable?
Whitlock KE, Postlethwait J, Ewer J. Whitlock KE, et al. Front Neuroendocrinol. 2019 Apr;53:100738. doi: 10.1016/j.yfrne.2019.02.002. Epub 2019 Feb 22. Front Neuroendocrinol. 2019. PMID: 30797802 Free PMC article. Review. - Kallmann syndrome: phenotype and genotype of hypogonadotropic hypogonadism.
Stamou MI, Georgopoulos NA. Stamou MI, et al. Metabolism. 2018 Sep;86:124-134. doi: 10.1016/j.metabol.2017.10.012. Epub 2017 Nov 3. Metabolism. 2018. PMID: 29108899 Free PMC article. Review.