Neural processing at the speed of smell - PubMed (original) (raw)
Editorial
. 2004 Dec 2;44(5):744-7.
doi: 10.1016/j.neuron.2004.11.024.
Affiliations
- PMID: 15572105
- DOI: 10.1016/j.neuron.2004.11.024
Free article
Editorial
Neural processing at the speed of smell
Rehan M Khan et al. Neuron. 2004.
Free article
Abstract
Olfaction is typically described as behaviorally slow, suggesting neural processes on the order of hundreds of milliseconds to seconds as candidate mechanisms in the creation of olfactory percepts. Whereas a recent study challenged this view in suggesting that a single sniff was sufficient for optimal olfactory discrimination, a study by Abraham et al. in this issue of Neuron sets out to negate the challenge by demonstrating increased processing time for discrimination of similar versus dissimilar stimuli. Here we reconcile both studies, which in our view together support the notion of a speed-accuracy tradeoff in olfactory discriminations that are made within about 200 ms. These findings are discussed in light of the challenges related to defining olfactory perceptual similarity in nonhuman animals.
Comment on
- Maintaining accuracy at the expense of speed: stimulus similarity defines odor discrimination time in mice.
Abraham NM, Spors H, Carleton A, Margrie TW, Kuner T, Schaefer AT. Abraham NM, et al. Neuron. 2004 Dec 2;44(5):865-76. doi: 10.1016/j.neuron.2004.11.017. Neuron. 2004. PMID: 15572116
Similar articles
- Perception without a thalamus how does olfaction do it?
Shepherd GM. Shepherd GM. Neuron. 2005 Apr 21;46(2):166-8. doi: 10.1016/j.neuron.2005.03.012. Neuron. 2005. PMID: 15848795 Review. - Speed and accuracy of olfactory discrimination in the rat.
Uchida N, Mainen ZF. Uchida N, et al. Nat Neurosci. 2003 Nov;6(11):1224-9. doi: 10.1038/nn1142. Epub 2003 Oct 19. Nat Neurosci. 2003. PMID: 14566341 - A truffle in the mouth is worth two in the bush: odor localization in the human brain.
Gottfried JA. Gottfried JA. Neuron. 2005 Aug 18;47(4):473-6. doi: 10.1016/j.neuron.2005.08.002. Neuron. 2005. PMID: 16102528 Review. - Perspectives on olfactory processing, conscious perception, and orbitofrontal cortex.
Shepherd GM. Shepherd GM. Ann N Y Acad Sci. 2007 Dec;1121:87-101. doi: 10.1196/annals.1401.032. Epub 2007 Sep 13. Ann N Y Acad Sci. 2007. PMID: 17872397 - Mechanisms of olfactory discrimination: converging evidence for common principles across phyla.
Hildebrand JG, Shepherd GM. Hildebrand JG, et al. Annu Rev Neurosci. 1997;20:595-631. doi: 10.1146/annurev.neuro.20.1.595. Annu Rev Neurosci. 1997. PMID: 9056726 Review.
Cited by
- Odor habituation can modulate very early olfactory event-related potential.
Kim K, Bae J, Jin Y, Moon C. Kim K, et al. Sci Rep. 2020 Oct 22;10(1):18117. doi: 10.1038/s41598-020-75263-7. Sci Rep. 2020. PMID: 33093624 Free PMC article. - Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice.
Abraham NM, Egger V, Shimshek DR, Renden R, Fukunaga I, Sprengel R, Seeburg PH, Klugmann M, Margrie TW, Schaefer AT, Kuner T. Abraham NM, et al. Neuron. 2010 Feb 11;65(3):399-411. doi: 10.1016/j.neuron.2010.01.009. Neuron. 2010. PMID: 20159452 Free PMC article. - Olfactory computations and network oscillation.
Gelperin A. Gelperin A. J Neurosci. 2006 Feb 8;26(6):1663-8. doi: 10.1523/JNEUROSCI.3737-05b.2006. J Neurosci. 2006. PMID: 16467512 Free PMC article. No abstract available. - A specific olfactory cortico-thalamic pathway contributing to sampling performance during odor reversal learning.
Courtiol E, Neiman M, Fleming G, Teixeira CM, Wilson DA. Courtiol E, et al. Brain Struct Funct. 2019 Mar;224(2):961-971. doi: 10.1007/s00429-018-1807-x. Epub 2018 Dec 1. Brain Struct Funct. 2019. PMID: 30506279 Free PMC article. - An Exception to Mental Simulation: No Evidence for Embodied Odor Language.
Speed LJ, Majid A. Speed LJ, et al. Cogn Sci. 2018 May;42(4):1146-1178. doi: 10.1111/cogs.12593. Epub 2018 Feb 14. Cogn Sci. 2018. PMID: 29442364 Free PMC article.