Hidden dynamics of vesicle adhesion induced by specific stickers - PubMed (original) (raw)

. 2004 Nov 26;93(22):228101.

doi: 10.1103/PhysRevLett.93.228101. Epub 2004 Nov 23.

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Hidden dynamics of vesicle adhesion induced by specific stickers

Damien Cuvelier et al. Phys Rev Lett. 2004.

Abstract

We experimentally studied the adhesion dynamics of vesicles decorated with specific stickers onto bioactive surfaces. The growth laws were found to strongly depend upon the chemical preparation of the substrate and were rationalized with theoretical descriptions based on scaling law arguments. By using a micropipette-free approach, we demonstrate that two-dimensional binding rates between receptor and ligand can be lower than three dimensional on rates by orders of magnitude due to reduced accessibility of the immobilized protein.

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