Cocaine use and withdrawal: the effect on sleep and mood - PubMed (original) (raw)
Cocaine use and withdrawal: the effect on sleep and mood
R Watson et al. Am J Drug Alcohol Abuse. 1992.
Abstract
Three recreational cocaine users (age, 26.7 years), after one adaptation night, spent 5 days and nights in the laboratory where their EEG, EOG, and submental EMG were recorded during all of their sleep. On the second afternoon and evening of the study, subjects used an estimated 1 to 2 g cocaine intranasally. They all slept between 2:00 A.M. and 9:00 A.M. that night. Blood samples were drawn each evening and morning. Absolute plasma cocaine levels and patterns of elimination were consistent with subjects report of dose and time of administration. Mood ratings were made repeatedly throughout the study. There was suppression of REM sleep during the use of cocaine followed by a rebound which is specific to REM sleep and is not seen in other stages of sleep. REM variables subsided to normal levels on the third recovery night following cocaine use.
Similar articles
- Electroencephalographic sleep and mood during cocaine withdrawal.
Kowatch RA, Schnoll SS, Knisely JS, Green D, Elswick RK. Kowatch RA, et al. J Addict Dis. 1992;11(4):21-45. doi: 10.1300/J069v11n04_03. J Addict Dis. 1992. PMID: 1486092 - The effects of cocaine on mood and sleep in cocaine-dependent males.
Johanson CE, Roehrs T, Schuh K, Warbasse L. Johanson CE, et al. Exp Clin Psychopharmacol. 1999 Nov;7(4):338-46. doi: 10.1037//1064-1297.7.4.338. Exp Clin Psychopharmacol. 1999. PMID: 10609968 Clinical Trial. - The effects of lisuride on mood and sleep during acute withdrawal in stimulant abusers: a preliminary report.
Gillin JC, Pulvirenti L, Withers N, Golshan S, Koob G. Gillin JC, et al. Biol Psychiatry. 1994 Jun 1;35(11):843-9. doi: 10.1016/0006-3223(94)90019-1. Biol Psychiatry. 1994. PMID: 8054406 Clinical Trial. - Effect of illicit recreational drugs upon sleep: cocaine, ecstasy and marijuana.
Schierenbeck T, Riemann D, Berger M, Hornyak M. Schierenbeck T, et al. Sleep Med Rev. 2008 Oct;12(5):381-9. doi: 10.1016/j.smrv.2007.12.004. Epub 2008 Mar 3. Sleep Med Rev. 2008. PMID: 18313952 Review. - Emergency room evaluation of cocaine-associated neuropsychiatric disorders.
Mendoza R, Miller BL, Mena I. Mendoza R, et al. Recent Dev Alcohol. 1992;10:73-87. doi: 10.1007/978-1-4899-1648-8_4. Recent Dev Alcohol. 1992. PMID: 1589608 Review.
Cited by
- Interaction between cocaine use and sleep behavior: A comprehensive review of cocaine's disrupting influence on sleep behavior and sleep disruptions influence on reward seeking.
Bjorness TE, Greene RW. Bjorness TE, et al. Pharmacol Biochem Behav. 2021 Jul;206:173194. doi: 10.1016/j.pbb.2021.173194. Epub 2021 May 1. Pharmacol Biochem Behav. 2021. PMID: 33940055 Free PMC article. Review. - Cognitive dysfunction in individuals with cocaine use disorder: Potential moderating factors and pharmacological treatments.
Mahoney JJ. Mahoney JJ. Exp Clin Psychopharmacol. 2019 Jun;27(3):203-214. doi: 10.1037/pha0000245. Epub 2018 Dec 17. Exp Clin Psychopharmacol. 2019. PMID: 30556731 Free PMC article. Review. - Repeated dosing with oral cocaine in humans: assessment of direct effects, withdrawal, and pharmacokinetics.
Walsh SL, Stoops WW, Moody DE, Lin SN, Bigelow GE. Walsh SL, et al. Exp Clin Psychopharmacol. 2009 Aug;17(4):205-16. doi: 10.1037/a0016469. Exp Clin Psychopharmacol. 2009. PMID: 19653786 Free PMC article. Clinical Trial. - Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review.
Angarita GA, Emadi N, Hodges S, Morgan PT. Angarita GA, et al. Addict Sci Clin Pract. 2016 Apr 26;11(1):9. doi: 10.1186/s13722-016-0056-7. Addict Sci Clin Pract. 2016. PMID: 27117064 Free PMC article. Review. - Sleep architecture, cocaine and visual learning.
Morgan PT, Pace-Schott EF, Sahul ZH, Coric V, Stickgold R, Malison RT. Morgan PT, et al. Addiction. 2008 Aug;103(8):1344-52. doi: 10.1111/j.1360-0443.2008.02233.x. Addiction. 2008. PMID: 18855824 Free PMC article. Clinical Trial.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical