Assessing computational tools for the discovery of transcription factor binding sites - PubMed (original) (raw)
Nan Li, Timothy L Bailey, George M Church, Bart De Moor, Eleazar Eskin, Alexander V Favorov, Martin C Frith, Yutao Fu, W James Kent, Vsevolod J Makeev, Andrei A Mironov, William Stafford Noble, Giulio Pavesi, Graziano Pesole, Mireille Régnier, Nicolas Simonis, Saurabh Sinha, Gert Thijs, Jacques van Helden, Mathias Vandenbogaert, Zhiping Weng, Christopher Workman, Chun Ye, Zhou Zhu
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- PMID: 15637633
- DOI: 10.1038/nbt1053
Free article
Assessing computational tools for the discovery of transcription factor binding sites
Martin Tompa et al. Nat Biotechnol. 2005 Jan.
Free article
Abstract
The prediction of regulatory elements is a problem where computational methods offer great hope. Over the past few years, numerous tools have become available for this task. The purpose of the current assessment is twofold: to provide some guidance to users regarding the accuracy of currently available tools in various settings, and to provide a benchmark of data sets for assessing future tools.
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