Opposite polarity of virus budding and of viral envelope glycoprotein distribution in epithelial cells derived from different tissues - PubMed (original) (raw)
Opposite polarity of virus budding and of viral envelope glycoprotein distribution in epithelial cells derived from different tissues
C Zurzolo et al. J Cell Biol. 1992 May.
Abstract
We compared the surface envelope glycoprotein distribution and the budding polarity of four RNA viruses in Fischer rat thyroid (FRT) cells and in CaCo-2 cells derived from a human colon carcinoma. Whereas both FRT and CaCo-2 cells sort similarly influenza hemagglutinin and vesicular stomatitis virus (VSV) G protein, respectively, to apical and basolateral membrane domains, they differ in their handling of two togaviruses, Sindbis and Semliki Forest virus (SFV). By conventional EM Sindbis virus and SFV were shown to bud apically in FRT cells and basolaterally in CaCo-2 cells. Consistent with this finding, the distribution of the p62/E2 envelope glycoprotein of SFV, assayed by immunoelectronmicroscopy and by domain-selective surface biotinylation was predominantly apical on FRT cells and basolateral on CaCo-2 cells. We conclude that a given virus and its envelope glycoprotein can be delivered to opposite membrane domains in epithelial cells derived from different tissues. The tissue specificity in the polarity of virus budding and viral envelope glycoprotein distribution indicate that the sorting machinery varies considerably between different epithelial cell types.
Similar articles
- A sorting signal for the basolateral delivery of the vesicular stomatitis virus (VSV) G protein lies in its luminal domain: analysis of the targeting of VSV G-influenza hemagglutinin chimeras.
Compton T, Ivanov IE, Gottlieb T, Rindler M, Adesnik M, Sabatini DD. Compton T, et al. Proc Natl Acad Sci U S A. 1989 Jun;86(11):4112-6. doi: 10.1073/pnas.86.11.4112. Proc Natl Acad Sci U S A. 1989. PMID: 2542964 Free PMC article. - Morphological and functional polarity of an epithelial thyroid cell line.
Nitsch L, Tramontano D, Ambesi-Impiombato FS, Quarto N, Bonatti S. Nitsch L, et al. Eur J Cell Biol. 1985 Jul;38(1):57-66. Eur J Cell Biol. 1985. PMID: 2992984 - Genesis of polarity in renal tubular cells.
Rodriguez-Boulan E. Rodriguez-Boulan E. Miner Electrolyte Metab. 1986;12(1):20-4. Miner Electrolyte Metab. 1986. PMID: 3007959 Review. - Membrane traffic in polarized neurons in culture.
de Hoop MJ, Dotti CG. de Hoop MJ, et al. J Cell Sci Suppl. 1993;17:85-92. doi: 10.1242/jcs.1993.supplement_17.13. J Cell Sci Suppl. 1993. PMID: 8144707 Review.
Cited by
- Characterization of a spontaneously polarizing HT-29 cell line, HT-29/cl.f8.
Mitchell DM, Ball JM. Mitchell DM, et al. In Vitro Cell Dev Biol Anim. 2004 Nov-Dec;40(10):297-302. doi: 10.1290/04100061.1. In Vitro Cell Dev Biol Anim. 2004. PMID: 15780006 - The alphaviruses: gene expression, replication, and evolution.
Strauss JH, Strauss EG. Strauss JH, et al. Microbiol Rev. 1994 Sep;58(3):491-562. doi: 10.1128/mr.58.3.491-562.1994. Microbiol Rev. 1994. PMID: 7968923 Free PMC article. Review. - Iminosugars: Promising therapeutics for influenza infection.
Tyrrell BE, Sayce AC, Warfield KL, Miller JL, Zitzmann N. Tyrrell BE, et al. Crit Rev Microbiol. 2017 Sep;43(5):521-545. doi: 10.1080/1040841X.2016.1242868. Epub 2016 Dec 8. Crit Rev Microbiol. 2017. PMID: 27931136 Free PMC article. Review. - Polar release of pathogenic Old World hantaviruses from renal tubular epithelial cells.
Krautkrämer E, Lehmann MJ, Bollinger V, Zeier M. Krautkrämer E, et al. Virol J. 2012 Nov 30;9:299. doi: 10.1186/1743-422X-9-299. Virol J. 2012. PMID: 23194647 Free PMC article. - Sorting of Marburg virus surface protein and virus release take place at opposite surfaces of infected polarized epithelial cells.
Sänger C, Mühlberger E, Ryabchikova E, Kolesnikova L, Klenk HD, Becker S. Sänger C, et al. J Virol. 2001 Feb;75(3):1274-83. doi: 10.1128/JVI.75.3.1274-1283.2001. J Virol. 2001. PMID: 11152500 Free PMC article.
References
- J Cell Biol. 1990 Sep;111(3):987-1000 - PubMed
- Int Rev Cytol Suppl. 1979;(10):163-72 - PubMed
- Science. 1990 May 11;248(4956):742-5 - PubMed
- J Cell Biol. 1990 Aug;111(2):347-59 - PubMed
- Cell. 1990 Feb 9;60(3):429-37 - PubMed