Healing after myocardial infarction - PubMed (original) (raw)
Review
Healing after myocardial infarction
Georg Ertl et al. Cardiovasc Res. 2005.
Abstract
Wounding and healing are archaic principles, prerequisite for survival of any biologic material. However, strategies to cope with wounding may be quite different among organisms, species, or among various organs of one species. Today, myocardial infarction and the consequent loss of fully functional myocardium is the major aetiology for heart failure. Despite aggressive primary therapy, prognosis remains serious in patients with large infarction and severe left ventricular dysfunction. Thus, it would be highly desirable to influence healing of the cardiac wound to maintain structure and function of the heart. Herein, we review different, important factors of cardiac healing including reperfusion, mechanical stress, gender, and neurohormonal factors as well as specific factors essential for healing which may be genetic or acquired, emphasizing similarities and discrepancies between different organs and species.
Similar articles
- Post-infarct remodelling: contribution of wound healing and inflammation.
Frantz S, Bauersachs J, Ertl G. Frantz S, et al. Cardiovasc Res. 2009 Feb 15;81(3):474-81. doi: 10.1093/cvr/cvn292. Epub 2008 Oct 31. Cardiovasc Res. 2009. PMID: 18977766 Free PMC article. Review. - Targeted deletion of nuclear factor kappaB p50 enhances cardiac remodeling and dysfunction following myocardial infarction.
Timmers L, van Keulen JK, Hoefer IE, Meijs MF, van Middelaar B, den Ouden K, van Echteld CJ, Pasterkamp G, de Kleijn DP. Timmers L, et al. Circ Res. 2009 Mar 13;104(5):699-706. doi: 10.1161/CIRCRESAHA.108.189746. Epub 2009 Jan 24. Circ Res. 2009. PMID: 19168865 - Inflammatory cytokines and postmyocardial infarction remodeling.
Nian M, Lee P, Khaper N, Liu P. Nian M, et al. Circ Res. 2004 Jun 25;94(12):1543-53. doi: 10.1161/01.RES.0000130526.20854.fa. Circ Res. 2004. PMID: 15217919 Review. - Age-related differences in repair of dermal wounds and myocardial infarcts attenuate during the later stages of healing.
Reed MJ, Karres N, Eyman D, Vernon RB, Edelberg JM. Reed MJ, et al. In Vivo. 2006 Nov-Dec;20(6B):801-6. In Vivo. 2006. PMID: 17203771 - Oxidative stress and left ventricular remodelling after myocardial infarction.
Hori M, Nishida K. Hori M, et al. Cardiovasc Res. 2009 Feb 15;81(3):457-64. doi: 10.1093/cvr/cvn335. Epub 2008 Dec 1. Cardiovasc Res. 2009. PMID: 19047340 Review.
Cited by
- Long-term engraftment and maturation of autologous iPSC-derived cardiomyocytes in two rhesus macaques.
Lin Y, Sato N, Hong S, Nakamura K, Ferrante EA, Yu ZX, Chen MY, Nakamura DS, Yang X, Clevenger RR, Hunt TJ, Taylor JL, Jeffries KR, Keeran KJ, Neidig LE, Mehta A, Schwartzbeck R, Yu SJ, Kelly C, Navarengom K, Takeda K, Adler SS, Choyke PL, Zou J, Murry CE, Boehm M, Dunbar CE. Lin Y, et al. Cell Stem Cell. 2024 Jul 5;31(7):974-988.e5. doi: 10.1016/j.stem.2024.05.005. Epub 2024 Jun 5. Cell Stem Cell. 2024. PMID: 38843830 - Inhibitory effect of microRNA-21 on pathways and mechanisms involved in cardiac fibrosis development.
Khalaji A, Mehrtabar S, Jabraeilipour A, Doustar N, Rahmani Youshanlouei H, Tahavvori A, Fattahi P, Alavi SMA, Taha SR, Fazlollahpour-Naghibi A, Shariat Zadeh M. Khalaji A, et al. Ther Adv Cardiovasc Dis. 2024 Jan-Dec;18:17539447241253134. doi: 10.1177/17539447241253134. Ther Adv Cardiovasc Dis. 2024. PMID: 38819836 Free PMC article. Review. - The Senescent Heart-"Age Doth Wither Its Infinite Variety".
Vijayakumar A, Wang M, Kailasam S. Vijayakumar A, et al. Int J Mol Sci. 2024 Mar 22;25(7):3581. doi: 10.3390/ijms25073581. Int J Mol Sci. 2024. PMID: 38612393 Free PMC article. Review. - Improved integration of single-cell transcriptome data demonstrates common and unique signatures of heart failure in mice and humans.
Jurado MR, Tombor LS, Arsalan M, Holubec T, Emrich F, Walther T, Abplanalp W, Fischer A, Zeiher AM, Schulz MH, Dimmeler S, John D. Jurado MR, et al. Gigascience. 2024 Jan 2;13:giae011. doi: 10.1093/gigascience/giae011. Gigascience. 2024. PMID: 38573186 Free PMC article. - Loss of Bone Morphogenetic Protein-9 Reduces Survival and Increases MMP Activity After Myocardial Infarction.
Bhave S, Esposito M, Swain L, Qiao X, Martin G, Wadhwa S, Everett K, Kapur NK. Bhave S, et al. JACC Basic Transl Sci. 2023 Aug 16;8(10):1318-1330. doi: 10.1016/j.jacbts.2023.05.017. eCollection 2023 Oct. JACC Basic Transl Sci. 2023. PMID: 38094696 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical