Linking epithelial-mesenchymal transition to the well-known polarity protein Par6 - PubMed (original) (raw)
Linking epithelial-mesenchymal transition to the well-known polarity protein Par6
Jean Paul Thiery et al. Dev Cell. 2005 Apr.
Free article
Abstract
Epithelial-mesenchymal transition (EMT) is involved in the formation of the body plan, tissue remodeling, and cancer progression. Two recent reports in Science (Barrios-Rodiles et al., 2005; Ozdamar et al., 2005) have decisively advanced our understanding of EMT. Par6 was identified as a key player in the control of tight junction (TJ) stability. This new study provides further insight into the protein networks involved in topologically regulated control of epithelial cell polarity and plasticity.
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