Is a vaccine needed against Candida albicans? - PubMed (original) (raw)
Review
Is a vaccine needed against Candida albicans?
A Brian Mochon et al. Med Mycol. 2005 Mar.
Erratum in
- Med Mycol. 2006 Mar;44(2):197
Abstract
The development of a useful Candida vaccine is a distinct possibility despite the fact that individuals with a lifetime of commensal sensitization do not develop sterile immunity to the organism. An effective Candida vaccine would be invaluable in preventing hematogenously disseminated candidiasis, as well as mucocutaneous disease. This review is a discussion of our current understanding of the interplay between commensal and pathogenic forms of Candida albicans and approaches toward active and passive immunoprevention against candidiasis.
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