Clusterin: the intriguing guises of a widely expressed glycoprotein - PubMed (original) (raw)
Review
Clusterin: the intriguing guises of a widely expressed glycoprotein
D E Jenne et al. Trends Biochem Sci. 1992 Apr.
Abstract
The glycoprotein clusterin has recently entered the scientific arena in diverse guises. It forms high-density lipoprotein complexes with apolipoprotein A-I, participates in the terminal complement reaction and serves as a granule constituent in neuronal and endocrine cells. Apically secreted, it is also found in the male reproductive tract and the tubular lumen of epithelial ducts. Thus, it may serve important functions in tissue remodelling, immune defense and transport of biologically active peptides.
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