Liquorice and hypertension - PubMed (original) (raw)

• PMID: 15869038

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Editorial

Liquorice and hypertension

S H van Uum. Neth J Med. 2005 Apr.

Free article

Abstract

Glycyrrhetinic acid, the active constituent of liquorice, inhibits renal IIbeta-hydroxysteroid dehydrogenase. This allows cortisol to stimulate mineralocorticoid receptors, which can result in hypertension and hypokalaemia. Treatment options are based on pathophysiological understanding.

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