The yeast Mediator complex and its regulation - PubMed (original) (raw)
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The yeast Mediator complex and its regulation
Stefan Björklund et al. Trends Biochem Sci. 2005 May.
Abstract
The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the basal RNA polymerase II transcription machinery. Mediator is required for the regulated transcription of nearly all RNA polymerase II-dependent genes in Saccharomyces cerevisiae, and post-translational modifications of specific Mediator subunits can affect global patterns of gene transcription.
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