Micros for microbes: non-coding regulatory RNAs in bacteria - PubMed (original) (raw)
Review
Micros for microbes: non-coding regulatory RNAs in bacteria
Susan Gottesman. Trends Genet. 2005 Jul.
Abstract
Small non-coding RNAs with important regulatory roles are not confined to eukaryotes. Recent studies have led to the identification of numerous small regulatory RNAs in Escherichia coli and in other bacteria. As in eukaryotic cells, a major class of these small RNAs acts by base-pairing with target mRNAs, resulting in changes in the translation and stability of the mRNA. Roles for these non-coding pairing RNAs in bacteria have been demonstrated in several cases. Because these non-coding RNAs act post-transcriptionally, they impose a regulatory step that is independent of and epistatic to any transcriptional signals for their target mRNAs.
Similar articles
- A conserved small RNA promotes discoordinate expression of the glmUS operon mRNA to activate GlmS synthesis.
Urban JH, Papenfort K, Thomsen J, Schmitz RA, Vogel J. Urban JH, et al. J Mol Biol. 2007 Oct 26;373(3):521-8. doi: 10.1016/j.jmb.2007.07.035. Epub 2007 Aug 2. J Mol Biol. 2007. PMID: 17854828 - Regulation of gene expression by small non-coding RNAs: a quantitative view.
Shimoni Y, Friedlander G, Hetzroni G, Niv G, Altuvia S, Biham O, Margalit H. Shimoni Y, et al. Mol Syst Biol. 2007;3:138. doi: 10.1038/msb4100181. Epub 2007 Sep 25. Mol Syst Biol. 2007. PMID: 17893699 Free PMC article. - Diversity of endogenous small non-coding RNAs in Oryza sativa.
Chen Z, Zhang J, Kong J, Li S, Fu Y, Li S, Zhang H, Li Y, Zhu Y. Chen Z, et al. Genetica. 2006 Sep-Nov;128(1-3):21-31. doi: 10.1007/s10709-005-2486-0. Genetica. 2006. PMID: 17028937 - Regulating bacterial transcription with small RNAs.
Storz G, Opdyke JA, Wassarman KM. Storz G, et al. Cold Spring Harb Symp Quant Biol. 2006;71:269-73. doi: 10.1101/sqb.2006.71.033. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381306 Review. - How to find small non-coding RNAs in bacteria.
Vogel J, Sharma CM. Vogel J, et al. Biol Chem. 2005 Dec;386(12):1219-38. doi: 10.1515/BC.2005.140. Biol Chem. 2005. PMID: 16336117 Review.
Cited by
- Computational identification of functional RNA homologs in metagenomic data.
Nawrocki EP, Eddy SR. Nawrocki EP, et al. RNA Biol. 2013 Jul;10(7):1170-9. doi: 10.4161/rna.25038. Epub 2013 May 20. RNA Biol. 2013. PMID: 23722291 Free PMC article. Review. - Quantification of the gene silencing performances of rationally-designed synthetic small RNAs.
Massaiu I, Pasotti L, Casanova M, Politi N, Zucca S, Cusella De Angelis MG, Magni P. Massaiu I, et al. Syst Synth Biol. 2015 Sep;9(3):107-23. doi: 10.1007/s11693-015-9177-7. Epub 2015 Aug 7. Syst Synth Biol. 2015. PMID: 26279705 Free PMC article. - Ten years of bacterial genome sequencing: comparative-genomics-based discoveries.
Binnewies TT, Motro Y, Hallin PF, Lund O, Dunn D, La T, Hampson DJ, Bellgard M, Wassenaar TM, Ussery DW. Binnewies TT, et al. Funct Integr Genomics. 2006 Jul;6(3):165-85. doi: 10.1007/s10142-006-0027-2. Epub 2006 May 12. Funct Integr Genomics. 2006. PMID: 16773396 Review. - An overview of RNAs with regulatory functions in gram-positive bacteria.
Romby P, Charpentier E. Romby P, et al. Cell Mol Life Sci. 2010 Jan;67(2):217-37. doi: 10.1007/s00018-009-0162-8. Epub 2009 Oct 27. Cell Mol Life Sci. 2010. PMID: 19859665 Free PMC article. Review. - Prokaryotic ncRNAs: Master regulators of gene expression.
Majumder R, Ghosh S, Das A, Singh MK, Samanta S, Saha A, Saha RP. Majumder R, et al. Curr Res Pharmacol Drug Discov. 2022 Oct 17;3:100136. doi: 10.1016/j.crphar.2022.100136. eCollection 2022. Curr Res Pharmacol Drug Discov. 2022. PMID: 36568271 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
Research Materials