Cell microarrays and RNA interference chip away at gene function - PubMed (original) (raw)
Review
. 2005 Jun:37 Suppl:S25-30.
doi: 10.1038/ng1560.
Affiliations
- PMID: 15920526
- DOI: 10.1038/ng1560
Review
Cell microarrays and RNA interference chip away at gene function
Douglas B Wheeler et al. Nat Genet. 2005 Jun.
Abstract
The recent development of cell microarrays offers the potential to accelerate high-throughput functional genetic studies. The widespread use of RNA interference (RNAi) has prompted several groups to fabricate RNAi cell microarrays that make possible discrete, in-parallel transfection with thousands of RNAi reagents on a microarray slide. Though still a budding technology, RNAi cell microarrays promise to increase the efficiency, economy and ease of genome-wide RNAi screens in metazoan cells.
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