CLIPs and CLASPs and cellular dynamics - PubMed (original) (raw)
Review
doi: 10.1038/nrm1664.
Affiliations
- PMID: 15928712
- DOI: 10.1038/nrm1664
Review
CLIPs and CLASPs and cellular dynamics
Niels Galjart. Nat Rev Mol Cell Biol. 2005 Jun.
Abstract
The dynamic properties of microtubules are regulated by plus-end tracking proteins (+TIPs), which associate with the distal ends of microtubules. Among the +TIPs are cytoplasmic linker proteins (CLIPs), which promote microtubule growth and regulate dynein-dynactin localization, and CLIP-associating proteins (CLASPs), which stabilize specific subsets of microtubules on reception of signalling cues. CLIPs and CLASPs interact and cooperate to direct the microtubule network, thereby regulating cellular asymmetry.
Similar articles
- Tracking the ends: a dynamic protein network controls the fate of microtubule tips.
Akhmanova A, Steinmetz MO. Akhmanova A, et al. Nat Rev Mol Cell Biol. 2008 Apr;9(4):309-22. doi: 10.1038/nrm2369. Epub 2008 Mar 5. Nat Rev Mol Cell Biol. 2008. PMID: 18322465 Review. - CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.
Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, Sasaki H, Matsui C, Severin F, Galjart N, Grosveld F, Vorobjev I, Tsukita S, Akhmanova A. Mimori-Kiyosue Y, et al. J Cell Biol. 2005 Jan 3;168(1):141-53. doi: 10.1083/jcb.200405094. J Cell Biol. 2005. PMID: 15631994 Free PMC article. - Structural basis of EB1 effects on microtubule dynamics.
Coquelle FM, Vitre B, Arnal I. Coquelle FM, et al. Biochem Soc Trans. 2009 Oct;37(Pt 5):997-1001. doi: 10.1042/BST0370997. Biochem Soc Trans. 2009. PMID: 19754439 Review. - An EB1-binding motif acts as a microtubule tip localization signal.
Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, Grigoriev I, van Rijssel FJ, Buey RM, Lawera A, Jelesarov I, Winkler FK, Wüthrich K, Akhmanova A, Steinmetz MO. Honnappa S, et al. Cell. 2009 Jul 23;138(2):366-76. doi: 10.1016/j.cell.2009.04.065. Cell. 2009. PMID: 19632184 - History-dependent catastrophes regulate axonal microtubule behavior.
Stepanova T, Smal I, van Haren J, Akinci U, Liu Z, Miedema M, Limpens R, van Ham M, van der Reijden M, Poot R, Grosveld F, Mommaas M, Meijering E, Galjart N. Stepanova T, et al. Curr Biol. 2010 Jun 8;20(11):1023-8. doi: 10.1016/j.cub.2010.04.024. Epub 2010 May 13. Curr Biol. 2010. PMID: 20471267
Cited by
- Podosome dynamics and location in vascular smooth muscle cells require CLASP-dependent microtubule bending.
Zhu X, Efimova N, Arnette C, Hanks SK, Kaverina I. Zhu X, et al. Cytoskeleton (Hoboken). 2016 Jun;73(6):300-15. doi: 10.1002/cm.21302. Epub 2016 May 20. Cytoskeleton (Hoboken). 2016. PMID: 27105779 Free PMC article. - Dynamics of Kv1 channel transport in axons.
Gu Y, Gu C. Gu Y, et al. PLoS One. 2010 Aug 4;5(8):e11931. doi: 10.1371/journal.pone.0011931. PLoS One. 2010. PMID: 20694152 Free PMC article. - Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability.
Mori Y, Inoue Y, Tanaka S, Doda S, Yamanaka S, Fukuchi H, Terada Y. Mori Y, et al. PLoS One. 2015 Oct 20;10(10):e0140968. doi: 10.1371/journal.pone.0140968. eCollection 2015. PLoS One. 2015. PMID: 26485573 Free PMC article. - Nucleation and Dynamics of Golgi-derived Microtubules.
Sanders AA, Kaverina I. Sanders AA, et al. Front Neurosci. 2015 Nov 10;9:431. doi: 10.3389/fnins.2015.00431. eCollection 2015. Front Neurosci. 2015. PMID: 26617483 Free PMC article. Review. - Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein.
Kruse R, Krantz J, Barker N, Coletta RL, Rafikov R, Luo M, Højlund K, Mandarino LJ, Langlais PR. Kruse R, et al. Mol Cell Proteomics. 2017 Oct;16(10):1718-1735. doi: 10.1074/mcp.RA117.000011. Epub 2017 May 26. Mol Cell Proteomics. 2017. PMID: 28550165 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases