Systems biology for the virtual plant - PubMed (original) (raw)

Review

Systems biology for the virtual plant

Rodrigo A Gutiérrez et al. Plant Physiol. 2005 Jun.

No abstract available

PubMed Disclaimer

Figures

Figure 1.

Figure 1.

Systems biology for the Virtual Plant. The ultimate goal of systems biology applied to plant research is to generate a model of the plant as a whole that describes processes across all layers of biological organization (molecular, cellular, physiological, organismal, and ecological; peripheral spiral, dotted arrows). Systems biology embodies an iterative process of experimentation at a global level, data integration, system modeling, and generation of hypotheses (internal cycle, solid arrows). These hypotheses lead to the design of new experiments that start a new round of the cycle. Each iteration refines the model and deepens our biological understanding of the system. Ultimately, such models may be used in a predictive mode and applied to improving traits associated with agriculture.

Similar articles

Cited by

References

    1. Birnbaum K, Shasha DE, Wang JY, Jung JW, Lambert GM, Galbraith DW, Benfey PN (2003) A gene expression map of the Arabidopsis root. Science 302: 1956–1960 - PubMed
    1. Ideker T, Galitski T, Hood L (2001. a) A new approach to decoding life: systems biology. Annu Rev Genomics Hum Genet 2: 343–372 - PubMed
    1. Ideker T, Thorsson V, Ranish JA, Christmas R, Buhler J, Eng JK, Bumgarner R, Goodlett DR, Aebersold R, Hood L (2001. b) Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science 292: 929–934 - PubMed
    1. Karp PD (1996) A strategy for database interoperation. J Comput Biol 2: 573–586 - PubMed
    1. Kitano H (2001) Foundations of Systems Biology. MIT Press, Cambridge, MA

Publication types

MeSH terms

LinkOut - more resources