Paraneoplastic chorea with leukoencephalopathy presenting with obsessive-compulsive and behavioral disorder - PubMed (original) (raw)
Case Reports
. 2005 Nov;20(11):1523-7.
doi: 10.1002/mds.20570.
Affiliations
- PMID: 16037914
- DOI: 10.1002/mds.20570
Case Reports
Paraneoplastic chorea with leukoencephalopathy presenting with obsessive-compulsive and behavioral disorder
Susanne Muehlschlegel et al. Mov Disord. 2005 Nov.
Abstract
Chorea is a rare manifestation of paraneoplastic disease and is associated with CV2/CRMP-5 antibodies. Obsessive-compulsive disorder and large-scale white matter abnormalities on MRI have not been previously reported in association with these antibodies. We report on a case of CV2 paraneoplastic syndrome with obsessive-compulsive behavior preceding the motor manifestations of chorea with associated leukoencephalopathy on MRI. The literature on paraneoplastic chorea is reviewed.
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