Mobile genetic elements: the agents of open source evolution - PubMed (original) (raw)

Review

Mobile genetic elements: the agents of open source evolution

Laura S Frost et al. Nat Rev Microbiol. 2005 Sep.

Abstract

Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of DNA sequences in prokaryotic chromosomes that seem to have originated from other prokaryotes or eukaryotes. However, it is equally important to understand the agents that effect DNA movement: plasmids, bacteriophages and transposons. Although these agents occur in all prokaryotes, comprehensive genomics of the prokaryotic mobile gene pool or 'mobilome' lags behind other genomics initiatives owing to challenges that are distinct from cellular chromosomal analysis. Recent work shows promise of improved mobile genetic element (MGE) genomics and consequent opportunities to take advantage - and avoid the dangers - of these 'natural genetic engineers'. This review describes MGEs, their properties that are important in horizontal gene transfer, and current opportunities to advance MGE genomics.

PubMed Disclaimer

Similar articles

• Prokaryote genome fluidity: toward a system approach of the mobilome.
  Toussaint A, Chandler M. Toussaint A, et al. Methods Mol Biol. 2012;804:57-80. doi: 10.1007/978-1-61779-361-5_4. Methods Mol Biol. 2012. PMID: 22144148 Review.
• Horizontal gene transfer and mobile genetic elements in marine systems.
  Sobecky PA, Hazen TH. Sobecky PA, et al. Methods Mol Biol. 2009;532:435-53. doi: 10.1007/978-1-60327-853-9_25. Methods Mol Biol. 2009. PMID: 19271200 Review.
• Divergence of mobile genetic elements involved in the distribution of xenobiotic-catabolic capacity.
  Nojiri H, Shintani M, Omori T. Nojiri H, et al. Appl Microbiol Biotechnol. 2004 Apr;64(2):154-74. doi: 10.1007/s00253-003-1509-y. Epub 2003 Dec 20. Appl Microbiol Biotechnol. 2004. PMID: 14689248 Review.
• Molecular aspects of gene transfer and foreign DNA acquisition in prokaryotes with regard to safety issues.
  Brigulla M, Wackernagel W. Brigulla M, et al. Appl Microbiol Biotechnol. 2010 Apr;86(4):1027-41. doi: 10.1007/s00253-010-2489-3. Epub 2010 Feb 27. Appl Microbiol Biotechnol. 2010. PMID: 20191269 Review.
• Identification and characterization of a new conjugation/type IVA secretion system (trb/tra) of Legionella pneumophila Corby localized on two mobile genomic islands.
  Glöckner G, Albert-Weissenberger C, Weinmann E, Jacobi S, Schunder E, Steinert M, Hacker J, Heuner K. Glöckner G, et al. Int J Med Microbiol. 2008 Jul;298(5-6):411-28. doi: 10.1016/j.ijmm.2007.07.012. Epub 2007 Sep 20. Int J Med Microbiol. 2008. PMID: 17888731

Cited by

• Isolation and Characterization of vB_PagP-SK1, a T7-Like Phage Infecting Pantoea agglomerans.
  McDougall DL, Soutar CD, Perry BJ, Brown C, Alexander D, Yost CK, Stavrinides J. McDougall DL, et al. Phage (New Rochelle). 2020 Mar 1;1(1):45-56. doi: 10.1089/phage.2019.0012. Epub 2020 Feb 25. Phage (New Rochelle). 2020. PMID: 36147614 Free PMC article.
• Towards an engineering theory of evolution.
  Castle SD, Grierson CS, Gorochowski TE. Castle SD, et al. Nat Commun. 2021 Jun 7;12(1):3326. doi: 10.1038/s41467-021-23573-3. Nat Commun. 2021. PMID: 34099656 Free PMC article. Review.
• Comparative genomics of a vertically transmitted thiotrophic bacterial ectosymbiont and its close free-living relative.
  Espada-Hinojosa S, Karthäuser C, Srivastava A, Schuster L, Winter T, de Oliveira AL, Schulz F, Horn M, Sievert S, Bright M. Espada-Hinojosa S, et al. Mol Ecol Resour. 2024 Jan;24(1):e13889. doi: 10.1111/1755-0998.13889. Epub 2023 Nov 27. Mol Ecol Resour. 2024. PMID: 38010882 Free PMC article.
• The interplay between relatedness and horizontal gene transfer drives the evolution of plasmid-carried public goods.
  Mc Ginty SÉ, Lehmann L, Brown SP, Rankin DJ. Mc Ginty SÉ, et al. Proc Biol Sci. 2013 May 1;280(1761):20130400. doi: 10.1098/rspb.2013.0400. Print 2013 Jun 22. Proc Biol Sci. 2013. PMID: 23760639 Free PMC article.
• Molecular insights into the genome dynamics and interactions between core and acquired genomes of Vibrio cholerae.
  Pant A, Bag S, Saha B, Verma J, Kumar P, Banerjee S, Kumar B, Kumar Y, Desigamani A, Maiti S, Maiti TK, Banerjee SK, Bhadra RK, Koley H, Dutta S, Nair GB, Ramamurthy T, Das B. Pant A, et al. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23762-23773. doi: 10.1073/pnas.2006283117. Epub 2020 Sep 1. Proc Natl Acad Sci U S A. 2020. PMID: 32873641 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Nature Publishing Group

• Other Literature Sources

  • The Lens - Patent Citations Database