Fewer genes, more noncoding RNA - PubMed (original) (raw)

. 2005 Sep 2;309(5740):1529-30.

doi: 10.1126/science.1116800.

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Fewer genes, more noncoding RNA

Jean-Michel Claverie. Science. 2005.

Abstract

Recent studies showing that most "messenger" RNAs do not encode proteins finally explain the long-standing discrepancy between the small number of protein-coding genes found in vertebrate genomes and the much larger and ever-increasing number of polyadenylated transcripts identified by tag-sampling or microarray-based methods. Exploring the role and diversity of these numerous noncoding RNAs now constitutes a main challenge in transcription research.

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