Targeting myelomonocytic cells to revert inflammation-dependent cancer promotion - PubMed (original) (raw)
Review
Targeting myelomonocytic cells to revert inflammation-dependent cancer promotion
Mario P Colombo et al. Cancer Res. 2005.
Abstract
Tumor development and progression are strongly linked to inflammation and the presence of tumor-associated macrophages (TAMs). In murine tumors, antitumor activity can be achieved by targeting TAM recruitment, survival, activation, polarization, effector signaling, or extracellular matrix interactions. Thus, it may be possible to increase the efficacy of conventional cancer therapeutic strategies by targeting TAMs.
Similar articles
- Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation.
Solinas G, Germano G, Mantovani A, Allavena P. Solinas G, et al. J Leukoc Biol. 2009 Nov;86(5):1065-73. doi: 10.1189/jlb.0609385. Epub 2009 Sep 9. J Leukoc Biol. 2009. PMID: 19741157 Review. - Convergent pathways of macrophage polarization: The role of B cells.
Sica A, Porta C, Riboldi E, Locati M. Sica A, et al. Eur J Immunol. 2010 Aug;40(8):2131-3. doi: 10.1002/eji.201040736. Eur J Immunol. 2010. PMID: 20623553 - Pathophysiology of tumor-associated macrophages.
Yuan A, Chen JJ, Yang PC. Yuan A, et al. Adv Clin Chem. 2008;45:199-223. Adv Clin Chem. 2008. PMID: 18429498 Review. - p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance.
Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, Bottazzi B, Colombo MP, Mantovani A, Sica A. Saccani A, et al. Cancer Res. 2006 Dec 1;66(23):11432-40. doi: 10.1158/0008-5472.CAN-06-1867. Cancer Res. 2006. PMID: 17145890 - Arginine metabolism in tumor-associated macrophages in cutaneous malignant melanoma: evidence from human and experimental tumors.
Massi D, Marconi C, Franchi A, Bianchini F, Paglierani M, Ketabchi S, Miracco C, Santucci M, Calorini L. Massi D, et al. Hum Pathol. 2007 Oct;38(10):1516-25. doi: 10.1016/j.humpath.2007.02.018. Epub 2007 Jul 19. Hum Pathol. 2007. PMID: 17640716
Cited by
- The role of extracellular vesicles in cholangiocarcinoma tumor microenvironment.
Zhang N, Shu L, Liu Z, Shi A, Zhao L, Huang S, Sheng G, Yan Z, Song Y, Huang F, Tang Y, Zhang Z. Zhang N, et al. Front Pharmacol. 2024 Jan 10;14:1336685. doi: 10.3389/fphar.2023.1336685. eCollection 2023. Front Pharmacol. 2024. PMID: 38269274 Free PMC article. Review. - CD163 protein inhibits lipopolysaccharide-induced macrophage transformation from M2 to M1 involved in disruption of the TWEAK-Fn14 interaction.
Chen L, Mei W, Song J, Chen K, Ni W, Wang L, Li Z, Ge X, Su L, Jiang C, Liu B, Dai C. Chen L, et al. Heliyon. 2023 Dec 4;10(1):e23223. doi: 10.1016/j.heliyon.2023.e23223. eCollection 2024 Jan 15. Heliyon. 2023. PMID: 38148798 Free PMC article. - Effective Reversal of Macrophage Polarization by Inhibitory Combinations Predicted by a Boolean Protein-Protein Interaction Model.
Szegvari G, Dora D, Lohinai Z. Szegvari G, et al. Biology (Basel). 2023 Feb 27;12(3):376. doi: 10.3390/biology12030376. Biology (Basel). 2023. PMID: 36979068 Free PMC article. - Tumor-Infiltrating Myeloid Cells Co-Express TREM1 and TREM2 and Elevated TREM-1 Associates With Disease Progression in Renal Cell Carcinoma.
Ford JW, Gonzalez-Cotto M, MacFarlane AW 4th, Peri S, Howard OMZ, Subleski JJ, Ruth KJ, Haseebuddin M, Al-Saleem T, Yang Y, Rayman P, Rini B, Linehan WM, Finke J, Weiss JM, Campbell KS, McVicar DW. Ford JW, et al. Front Oncol. 2022 Feb 10;11:662723. doi: 10.3389/fonc.2021.662723. eCollection 2021. Front Oncol. 2022. PMID: 35223446 Free PMC article. - Myeloid cell heterogeneity in lung cancer: implication for immunotherapy.
Sangaletti S, Ferrara R, Tripodo C, Garassino MC, Colombo MP. Sangaletti S, et al. Cancer Immunol Immunother. 2021 Sep;70(9):2429-2438. doi: 10.1007/s00262-021-02916-5. Epub 2021 Apr 2. Cancer Immunol Immunother. 2021. PMID: 33797567 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources